Increased monocyte adhesion by endothelial expression of VCAM-1 missense variation in vitro

Abstract Objective In whole genome and single gene analyses, genetic variation at the vascular cell adhesion molecule-1 ( VCAM-1 ) locus has been associated with inflammatory disease and stroke in sickle cell anaemia. In the current work, we investigated the functional impact of VCAM-1 missense vari...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Atherosclerosis 2013-10, Vol.230 (2), p.185-190
Hauptverfasser:	Schmitz, Boris, Vischer, Peter, Brand, Eva, Schmidt-Petersen, Klaus, Korb-Pap, Adelheid, Guske, Katrin, Nedele, Johanna, Schelleckes, Michael, Hillen, Jan, Rötrige, Alois, Simmet, Thomas, Paul, Martin, Cambien, François, Brand, Stefan-Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion Alleles atherosclerosis Atherosclerosis - pathology Blotting, Western Cardiovascular Cardiovascular disease Cell Adhesion endothelial cells Endothelial Cells - cytology Endothelium, Vascular - pathology Enzyme-Linked Immunosorbent Assay Functional analyses genes genetic variation Humans Inflammation loci messenger RNA missense mutation Missense variants Monocyte adhesion Monocytes - cytology Mutation Mutation, Missense quantitative polymerase chain reaction Real-Time Polymerase Chain Reaction RNA, Messenger - metabolism sickle cell anemia stroke Time Factors U937 Cells Vascular Cell Adhesion Molecule-1 - genetics Vascular cell adhesion protein-1 Western blotting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!