A silk fibroin based hepatocarcinoma model and the assessment of the drug response in hyaluronan-binding protein 1 overexpressed HepG2 cells

Abstract Microenvironment around tumor cells plays an important role in its malignancy or invasiveness. Hyaluronan (HA), a major component of extracellular matrix is found to be elevated in most of cancerous niche/microenvironment and performs regulatory role in the progression of tumors and metasta...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomaterials 2013-12, Vol.34 (37), p.9462-9474
Hauptverfasser:	Kundu, Banani, Saha, Paramita, Datta, Kasturi, Kundu, Subhas C
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Methylumbelliferone Advanced Basic Science Animals Antineoplastic Agents - pharmacology Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology Carrier Proteins - genetics Dentistry Drug screening Drug Screening Assays, Antitumor - methods Fibroins - chemistry Hep G2 Cells - drug effects Hep G2 Cells - metabolism Hep G2 Cells - pathology Humans Hyaluronan-binding protein 1 Hymecromone - pharmacology Liver Neoplasms - drug therapy Liver Neoplasms - genetics Liver Neoplasms - pathology Mitochondrial Proteins - genetics Scaffold Silk fibroin Tissue Scaffolds - chemistry Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!