Tritiated peptides: Part 16. Synthesis of ( super(3)H-Tyr super(8))-physalaemin

Tritiated peptides: Part 16. Synthesis of ( super(3)H-Tyr super(8))-physalaemin

The title compound was synthesised with a specific activity of 30 Ci mmol super(-1) and with radiochemical purity of 96% by iodination of the sulphoxide followed by catalytic tritiation of an isolated fraction. Iodination and reduction studies on model peptides are reported. Alternative philosophies...

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Veröffentlicht in:Journal of labelled compounds & radiopharmaceuticals 1986-01, Vol.23 (1), p.9-20
Hauptverfasser: Brundish, DE, Wade, R
Format: Artikel
Sprache:eng
Schlagworte:
( superH-Tyr super)-physalaemin
peptide synthesis
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Zusammenfassung:The title compound was synthesised with a specific activity of 30 Ci mmol super(-1) and with radiochemical purity of 96% by iodination of the sulphoxide followed by catalytic tritiation of an isolated fraction. Iodination and reduction studies on model peptides are reported. Alternative philosophies for preparing tritiated peptides are critically discussed.
ISSN:0362-4803