Defining adrenal status with salivary cortisol by gold-standard insulin hypoglycemia

Insulin-induced hypoglycemia (IHT) is considered the gold standard test for evaluating the HPA axis. Serum free cortisol or its surrogate, salivary cortisol as opposed to total cortisol concentrations, offers a better reflection of the activation of HPA axis. Our study aimed to derive reference rang...

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Veröffentlicht in:	Clinical biochemistry 2013-10, Vol.46 (15), p.1442-1446
Hauptverfasser:	Karpman, Matthew S., Neculau, Madalina, Dias, Valerian C., Kline, Gregory A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal function Adrenal Glands - metabolism Adrenal Glands - physiopathology Adrenal insufficiency Adrenal Insufficiency - diagnosis Adrenal Insufficiency - metabolism Adrenal Insufficiency - physiopathology Adult Aged Female Free cortisol Humans Hydrocortisone - metabolism Hypoglycemia - chemically induced Hypoglycemia - metabolism Hypoglycemia - physiopathology Hypothalamo-Hypophyseal System - metabolism Hypothalamo-Hypophyseal System - physiopathology Insulin Insulin hypoglycemia test Male Middle Aged Pituitary-Adrenal System - metabolism Pituitary-Adrenal System - physiopathology Regression Analysis Salivary cortisol Salivary Glands - chemistry Sensitivity and Specificity
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