The expression and localization of leptin and its receptor in goat ovarian follicles

Leptin, a hormone that was originally identified in adipocytes, has been implicated in the regulation of ovarian folliculogenesis through endocrine, autocrine and/or paracrine mechanisms. The aim of this study was to investigate the expression patterns of leptin (LEP) and its receptor (LEPRb) in dif...

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Veröffentlicht in:	Animal reproduction science 2013-10, Vol.141 (3-4), p.142-147
Hauptverfasser:	Batista, A.M, Silva, D.M.F, Rêgo, M.J.B.M, Silva, F.L.M, Silva, E.C.B, Beltrão, E.I.C, Gomes Filho, M.A, Wischral, A, Guerra, M.M.P
Format:	Artikel
Sprache:	eng
Schlagworte:	adipocytes Animals cytoplasm developmental stages Female follicular development Gene expression Gene Expression Regulation - physiology Goat ovary goats Goats - metabolism granulosa cells Immunohistochemistry Leptin Leptin - genetics Leptin - metabolism Leptin receptor messenger RNA oocytes Ovarian Follicle - cytology Ovarian Follicle - metabolism Protein Transport proteins Receptors, Leptin - genetics Receptors, Leptin - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Signal Transduction
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Beschreibung
Zusammenfassung:	Leptin, a hormone that was originally identified in adipocytes, has been implicated in the regulation of ovarian folliculogenesis through endocrine, autocrine and/or paracrine mechanisms. The aim of this study was to investigate the expression patterns of leptin (LEP) and its receptor (LEPRb) in different types of ovarian follicular cells from goats. In small follicles, the expression levels of LEP were higher (P
ISSN:	0378-4320 1873-2232
DOI:	10.1016/j.anireprosci.2013.08.007