Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits

The aim of the present study was to explore the role of variations with modest effects (previously identified by a large-scale meta-analysis in European populations) in the genetic background of type 2 diabetes (T2D) and diabetes-related traits in a Japanese population. We enrolled 2632 Japanese sub...

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Veröffentlicht in:	Journal of human genetics 2012-12, Vol.57 (12), p.776-779
Hauptverfasser:	Fujita, Hayato, Hara, Kazuo, Shojima, Nobuhiro, Horikoshi, Momoko, Iwata, Minoru, Hirota, Yushi, Tobe, Kazuyuki, Seino, Susumu, Kadowaki, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles Asian Continental Ancestry Group - genetics Biomarkers - analysis Blood Glucose - metabolism Case-Control Studies Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Insulin - metabolism Insulin-like growth factor I Middle Aged Phenotype Polymorphism, Single Nucleotide - genetics Population genetics Risk Factors Single-nucleotide polymorphism
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