Abnormal p38  mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation

We previously interrogated the transcriptome in heart tissue from Lmna super(H222P/H222P) mice, a mouse model of cardiomyopathy caused by lamin A/C gene (LMNA) mutation, and found that the extracellular signal-regulated kinase 1/2 and Jun N-terminal kinase branches of the mitogen-activated protein (...

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Veröffentlicht in:Human molecular genetics 2012-10, Vol.21 (19), p.4325-4333
Hauptverfasser: Muchir, A., Wu, W., Choi, J. C., Iwata, S., Morrow, J., Homma, S., Worman, H. J.
Format: Artikel
Sprache:eng
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