High gas pressure: An innovative method for the inactivation of dried bacterial spores

In this article, an original non‐thermal process to inactivate dehydrated bacterial spores is described. The use of gases such as nitrogen or argon as transmission media under high isostatic pressure led to an inactivation of over 2 logs CFU/g of Bacillus subtilis spores at 430 MPa, room temperature...

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Veröffentlicht in:	Biotechnology and bioengineering 2012-08, Vol.109 (8), p.1996-2004
Hauptverfasser:	Colas de la Noue, A., Espinasse, V., Perrier-Cornet, J.-M., Gervais, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Argon - pharmacology Bacillus subtilis Bacillus subtilis - drug effects Bacillus subtilis - physiology bacterial spores Colony Count, Microbial Desiccation Disinfectants - pharmacology Gases germination Gram-positive bacteria high pressure Hydrostatic Pressure inactivation inert gas Microbial Viability Nitrogen - pharmacology Noble Gases - pharmacology Permeability Porosity Pressure Sorption Spores, Bacterial - drug effects Spores, Bacterial - physiology
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