Skeletal age assessment in children using an open compact MRI system
MRI may be a noninvasive and alternative tool for skeletal age assessment in children, although few studies have reported on this topic. In this article, skeletal age was assessed over a wide range of ages using an open, compact MRI optimized for the imaging of a child's hand and wrist, and its...
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Veröffentlicht in: | Magnetic resonance in medicine 2013-06, Vol.69 (6), p.1697-1702 |
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creator | Terada, Yasuhiko Kono, Saki Tamada, Daiki Uchiumi, Tomomi Kose, Katsumi Miyagi, Ryo Yamabe, Eiko Yoshioka, Hiroshi |
description | MRI may be a noninvasive and alternative tool for skeletal age assessment in children, although few studies have reported on this topic. In this article, skeletal age was assessed over a wide range of ages using an open, compact MRI optimized for the imaging of a child's hand and wrist, and its validity was evaluated. MR images and their three‐dimensional segmentation visualized detailed skeletal features of each bone in the hand and wrist. Skeletal age was then independently scored from the MR images by two raters, according to the Tanner–Whitehouse Japan system. The skeletal age assessed by MR rating demonstrated a strong positive correlation with chronological age. The intrarater and inter‐rater reproducibilities were significantly high. These results demonstrate the validity and reliability of skeletal age assessment using MRI. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc. |
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In this article, skeletal age was assessed over a wide range of ages using an open, compact MRI optimized for the imaging of a child's hand and wrist, and its validity was evaluated. MR images and their three‐dimensional segmentation visualized detailed skeletal features of each bone in the hand and wrist. Skeletal age was then independently scored from the MR images by two raters, according to the Tanner–Whitehouse Japan system. The skeletal age assessed by MR rating demonstrated a strong positive correlation with chronological age. The intrarater and inter‐rater reproducibilities were significantly high. These results demonstrate the validity and reliability of skeletal age assessment using MRI. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.</description><identifier>ISSN: 0740-3194</identifier><identifier>EISSN: 1522-2594</identifier><identifier>DOI: 10.1002/mrm.24439</identifier><identifier>PMID: 22851444</identifier><identifier>CODEN: MRMEEN</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Age Determination by Skeleton - instrumentation ; Age Determination by Skeleton - methods ; Aging - pathology ; Aging - physiology ; Child ; Child, Preschool ; Equipment Design ; Equipment Failure Analysis ; Female ; Hand Bones - anatomy & histology ; Hand Bones - growth & development ; Humans ; Image Interpretation, Computer-Assisted - methods ; imaging technique ; Magnetic Resonance Imaging - methods ; Male ; Miniaturization ; Observer Variation ; open compact MRI ; pediatrics ; Reproducibility of Results ; Sensitivity and Specificity ; skeletal age assessment</subject><ispartof>Magnetic resonance in medicine, 2013-06, Vol.69 (6), p.1697-1702</ispartof><rights>Copyright © 2012 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5539-370a57e6d8496286717e1092c70f27e3494bf0989ad62cf7a7699f5557e7250e3</citedby><cites>FETCH-LOGICAL-c5539-370a57e6d8496286717e1092c70f27e3494bf0989ad62cf7a7699f5557e7250e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmrm.24439$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmrm.24439$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,1434,27926,27927,45576,45577,46411,46835</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22851444$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Terada, Yasuhiko</creatorcontrib><creatorcontrib>Kono, Saki</creatorcontrib><creatorcontrib>Tamada, Daiki</creatorcontrib><creatorcontrib>Uchiumi, Tomomi</creatorcontrib><creatorcontrib>Kose, Katsumi</creatorcontrib><creatorcontrib>Miyagi, Ryo</creatorcontrib><creatorcontrib>Yamabe, Eiko</creatorcontrib><creatorcontrib>Yoshioka, Hiroshi</creatorcontrib><title>Skeletal age assessment in children using an open compact MRI system</title><title>Magnetic resonance in medicine</title><addtitle>Magn Reson Med</addtitle><description>MRI may be a noninvasive and alternative tool for skeletal age assessment in children, although few studies have reported on this topic. In this article, skeletal age was assessed over a wide range of ages using an open, compact MRI optimized for the imaging of a child's hand and wrist, and its validity was evaluated. MR images and their three‐dimensional segmentation visualized detailed skeletal features of each bone in the hand and wrist. Skeletal age was then independently scored from the MR images by two raters, according to the Tanner–Whitehouse Japan system. The skeletal age assessed by MR rating demonstrated a strong positive correlation with chronological age. The intrarater and inter‐rater reproducibilities were significantly high. These results demonstrate the validity and reliability of skeletal age assessment using MRI. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.</description><subject>Adolescent</subject><subject>Age Determination by Skeleton - instrumentation</subject><subject>Age Determination by Skeleton - methods</subject><subject>Aging - pathology</subject><subject>Aging - physiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Female</subject><subject>Hand Bones - anatomy & histology</subject><subject>Hand Bones - growth & development</subject><subject>Humans</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>imaging technique</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Miniaturization</subject><subject>Observer Variation</subject><subject>open compact MRI</subject><subject>pediatrics</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>skeletal age assessment</subject><issn>0740-3194</issn><issn>1522-2594</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcuOEzEQRS0EYjKBBT-ALLFhFp2UX-32knkQIiUhBBBLy9OpDp3pR7C7Bfl7DHkskICVVdK5R-W6hLxgMGIAfFz7esSlFOYRGTDFecKVkY_JALSERDAjL8hlCFsAMEbLp-SC80wxKeWA3H58wAo7V1G3QepCwBBqbDpaNjT_WlZrjw3tQ9lsqGtou4tT3tY7l3d0vprSsA8d1s_Ik8JVAZ8f3yH5_Pbu0827ZPZ-Mr15M0typYRJhAanNKbrTJqUZ6lmGhkYnmsouEYhjbwvwGTGrVOeF9rp1JhCqZjRXAGKIXl98O58-63H0Nm6DDlWlWuw7YNlUkhgGQf1f1QoAfECxkT01R_otu19Ez8ShUzH1SGFf1JCsSxjSqSRujpQuW9D8FjYnS9r5_eWgf3VlY1d2d9dRfbl0djf17g-k6dyIjA-AN_LCvd_N9n5an5SJodEGWv5cU44_2BTLbSyXxYTu1ya6_kHxuxC_ATfN6gt</recordid><startdate>201306</startdate><enddate>201306</enddate><creator>Terada, Yasuhiko</creator><creator>Kono, Saki</creator><creator>Tamada, Daiki</creator><creator>Uchiumi, Tomomi</creator><creator>Kose, Katsumi</creator><creator>Miyagi, Ryo</creator><creator>Yamabe, Eiko</creator><creator>Yoshioka, Hiroshi</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope><scope>7QO</scope></search><sort><creationdate>201306</creationdate><title>Skeletal age assessment in children using an open compact MRI system</title><author>Terada, Yasuhiko ; Kono, Saki ; Tamada, Daiki ; Uchiumi, Tomomi ; Kose, Katsumi ; Miyagi, Ryo ; Yamabe, Eiko ; Yoshioka, Hiroshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5539-370a57e6d8496286717e1092c70f27e3494bf0989ad62cf7a7699f5557e7250e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Age Determination by Skeleton - instrumentation</topic><topic>Age Determination by Skeleton - methods</topic><topic>Aging - pathology</topic><topic>Aging - physiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Female</topic><topic>Hand Bones - anatomy & histology</topic><topic>Hand Bones - growth & development</topic><topic>Humans</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>imaging technique</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Miniaturization</topic><topic>Observer Variation</topic><topic>open compact MRI</topic><topic>pediatrics</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>skeletal age assessment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Terada, Yasuhiko</creatorcontrib><creatorcontrib>Kono, Saki</creatorcontrib><creatorcontrib>Tamada, Daiki</creatorcontrib><creatorcontrib>Uchiumi, Tomomi</creatorcontrib><creatorcontrib>Kose, Katsumi</creatorcontrib><creatorcontrib>Miyagi, Ryo</creatorcontrib><creatorcontrib>Yamabe, Eiko</creatorcontrib><creatorcontrib>Yoshioka, Hiroshi</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><jtitle>Magnetic resonance in medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Terada, Yasuhiko</au><au>Kono, Saki</au><au>Tamada, Daiki</au><au>Uchiumi, Tomomi</au><au>Kose, Katsumi</au><au>Miyagi, Ryo</au><au>Yamabe, Eiko</au><au>Yoshioka, Hiroshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Skeletal age assessment in children using an open compact MRI system</atitle><jtitle>Magnetic resonance in medicine</jtitle><addtitle>Magn Reson Med</addtitle><date>2013-06</date><risdate>2013</risdate><volume>69</volume><issue>6</issue><spage>1697</spage><epage>1702</epage><pages>1697-1702</pages><issn>0740-3194</issn><eissn>1522-2594</eissn><coden>MRMEEN</coden><abstract>MRI may be a noninvasive and alternative tool for skeletal age assessment in children, although few studies have reported on this topic. In this article, skeletal age was assessed over a wide range of ages using an open, compact MRI optimized for the imaging of a child's hand and wrist, and its validity was evaluated. MR images and their three‐dimensional segmentation visualized detailed skeletal features of each bone in the hand and wrist. Skeletal age was then independently scored from the MR images by two raters, according to the Tanner–Whitehouse Japan system. The skeletal age assessed by MR rating demonstrated a strong positive correlation with chronological age. The intrarater and inter‐rater reproducibilities were significantly high. These results demonstrate the validity and reliability of skeletal age assessment using MRI. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>22851444</pmid><doi>10.1002/mrm.24439</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Age Determination by Skeleton - instrumentation Age Determination by Skeleton - methods Aging - pathology Aging - physiology Child Child, Preschool Equipment Design Equipment Failure Analysis Female Hand Bones - anatomy & histology Hand Bones - growth & development Humans Image Interpretation, Computer-Assisted - methods imaging technique Magnetic Resonance Imaging - methods Male Miniaturization Observer Variation open compact MRI pediatrics Reproducibility of Results Sensitivity and Specificity skeletal age assessment |
title | Skeletal age assessment in children using an open compact MRI system |
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