Proteomic profiling of expression of proteasomal subunits from livers of mice treated with diethylnitrosamine

The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Diethylnitrosamine is metabolized primarily in the liver by cytochrome P‐450 and can cause DNA damage. The 26S proteasome is a large proteolytic complex that degrades ubiquitin...

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Veröffentlicht in:	Proteomics (Weinheim) 2013-01, Vol.13 (2), p.389-397
Hauptverfasser:	Yuan, Fuqiang, Lu, Jia, You, Pan, Yang, Zengming, Yang, Pengyuan, Ma, Qiling, Tao, Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animal proteomics Animals Biological and medical sciences Diethylnitrosamine Electrophoresis, Gel, Two-Dimensional Expression Fundamental and applied biological sciences. Psychology Histocytochemistry Hyperplasia Liver Liver - chemistry Liver - drug effects Liver - enzymology Liver - pathology Liver lesion Male Mice Miscellaneous Polymerase Chain Reaction Proteasome Proteasome Endopeptidase Complex - biosynthesis Proteasome Endopeptidase Complex - genetics Proteasome Endopeptidase Complex - metabolism Protein Subunits Proteins Proteome - chemistry Proteome - drug effects Proteome - genetics Proteome - metabolism Proteomics - methods
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