Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker

AM94 is a fluorinated analog of biphalin with non‐hydrazine linker that has an in vitro affinity for μ‐opioid and δ‐opioid receptors tenfold higher than biphalin. Furthermore, in vivo evaluation in rats showed that AM94 has in hot plate test – after both intracerebroventricular and intravenous admin...

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