Osteoconductive action of alendronate after implantation of beta tricalcium phosphate in rat adjuvant-induced arthritis

The aim of the study was to determine the effect of alendronate on resorption of β-tricalcium phosphate (β-TCP) and bone formation in rats with adjuvant-induced arthritis (AIA). After preparation of a model of AIA in rats (day 0), alendronate or vehicle was injected intraperitoneally once daily five...

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Veröffentlicht in:	Journal of bone and mineral metabolism 2012-11, Vol.30 (6), p.609-618
Hauptverfasser:	Netsu, Takahiro, Kondo, Naoki, Arai, Katsumitsu, Ogose, Akira, Endo, Naoto
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Alendronate - pharmacology Animals Arthritis, Experimental - drug therapy Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Calcification, Physiologic Calcium Phosphates - metabolism Collagen Type I - biosynthesis Diseases of the osteoarticular system Inflammatory joint diseases Isoenzymes - metabolism Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Original Article Orthopedics Osteocalcin - blood Osteogenesis - drug effects Pharmacology. Drug treatments Rats Tartrate-Resistant Acid Phosphatase
Online-Zugang:	Volltext
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