Region-dependent and stage-specific effects of stress, environmental enrichment, and antidepressant treatment on hippocampal neurogenesis

ABSTRACT Chronic stress and depression are associated with decreased levels of hippocampal neurogenesis. On the other hand, antidepressants as well as environmental enrichment may rely in part on their pro‐neurogenic effects to improve cognition and mood. Because a functional heterogeneity has been...

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Veröffentlicht in:	Hippocampus 2013-09, Vol.23 (9), p.797-811
Hauptverfasser:	Tanti, Arnaud, Westphal, Willy-Paul, Girault, Virginie, Brizard, Bruno, Devers, Severine, Leguisquet, Anne-Marie, Surget, Alexandre, Belzung, Catherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals antidepressants Antidepressive Agents - therapeutic use Bromodeoxyuridine - metabolism Calbindin 2 - metabolism Cell Count chronic stress depression Disease Models, Animal Environment environmental enrichment Fluoxetine - therapeutic use hippocampal neurogenesis Hippocampus - drug effects Hippocampus - pathology Homeodomain Proteins - metabolism Ki-67 Antigen - metabolism Male Mice Mice, Inbred BALB C Microtubule-Associated Proteins - metabolism Neurogenesis - drug effects Neurogenesis - physiology Neuropeptides - metabolism septo-temporal axis Stress, Psychological - drug therapy Stress, Psychological - nursing Stress, Psychological - pathology Tumor Suppressor Proteins - metabolism
Online-Zugang:	Volltext
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