Hospital-acquired anemia: Prevalence, outcomes, and healthcare implications
BACKGROUND Evidence suggests that patients with normal hemoglobin (Hgb) levels on hospital admission who subsequently develop hospital‐acquired anemia (HAA) may be at risk for adverse outcomes. Our objectives were to (1) determine the prevalence of HAA and (2) examine whether HAA is associated with...
Gespeichert in:
| Veröffentlicht in: | Journal of hospital medicine 2013-09, Vol.8 (9), p.506-512 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 512 |
|---|---|
| container_issue | 9 |
| container_start_page | 506 |
| container_title | Journal of hospital medicine |
| container_volume | 8 |
| creator | Koch, Colleen G. Li, Liang Sun, Zhiyuan Hixson, Eric D. Tang, Anne Phillips, Shannon C. Blackstone, Eugene H. Henderson, J. Michael |
| description | BACKGROUND
Evidence suggests that patients with normal hemoglobin (Hgb) levels on hospital admission who subsequently develop hospital‐acquired anemia (HAA) may be at risk for adverse outcomes. Our objectives were to (1) determine the prevalence of HAA and (2) examine whether HAA is associated with increased mortality, length of stay (LOS), and total hospital charges.
METHODS
The population consisted of 417,301 adult hospitalizations from January 1, 2009 to August 31, 2011, in an academic medical center and 9 community hospitals. Patients with anemia on admission, and hospitals in the health system without available laboratory data were excluded; 188,447 hospitalizations were included in the analysis. Demographics, comorbidities, and outcomes were retrieved from administrative data; Hgb values were taken from the electronic medical record. Regression modeling was used to examine the association between demographics, comorbidity, hospitalization type, and HAA variables (mild: Hgb >11 and 11 and |
| doi_str_mv | 10.1002/jhm.2061 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1433272903</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3063884411</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4211-4352a14b98f8486fa48217690251284565778e378e1f93ba4818ad8cdbf35af3</originalsourceid><addsrcrecordid>eNp1kF1LwzAUhoMobk7BXyAFb7xYNZ9t4p3Mj6lTdzH0MmRpyjLbdUtadf_eDLcJgheHc-B9eDi8ABwjeI4gxBfTSXmOYYJ2QBsxRmKWwGR3czOBW-DA-ymElHBG90ELE56SlIg2eOxXfm5rVcRKLxrrTBapmSmtuoyGznyowsy06UZVU-uqNL4b0iyaGFXUE62ciWw5L6xWta1m_hDs5arw5mi9O2B0ezPq9ePBy91972oQa4oRiilhWCE6FjznlCe5ohyjNBEQM4Q5ZQlLU25IGJQLMg4x4irjOhvnhKmcdMDZj3buqkVjfC1L67UpivB41XiJKCE4xQKSgJ7-QadV42bhuRUFSQK5SH-F2lXeO5PLubOlckuJoFz1K0O_ctVvQE_WwmZcmmwLbgoNQPwDfNrCLP8VyYf-01q45q2vzdeWV-5dJsHI5NvznXx6RQwNr4UU5BvvXpCW</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1430360897</pqid></control><display><type>article</type><title>Hospital-acquired anemia: Prevalence, outcomes, and healthcare implications</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Koch, Colleen G. ; Li, Liang ; Sun, Zhiyuan ; Hixson, Eric D. ; Tang, Anne ; Phillips, Shannon C. ; Blackstone, Eugene H. ; Henderson, J. Michael</creator><creatorcontrib>Koch, Colleen G. ; Li, Liang ; Sun, Zhiyuan ; Hixson, Eric D. ; Tang, Anne ; Phillips, Shannon C. ; Blackstone, Eugene H. ; Henderson, J. Michael</creatorcontrib><description><![CDATA[BACKGROUND
Evidence suggests that patients with normal hemoglobin (Hgb) levels on hospital admission who subsequently develop hospital‐acquired anemia (HAA) may be at risk for adverse outcomes. Our objectives were to (1) determine the prevalence of HAA and (2) examine whether HAA is associated with increased mortality, length of stay (LOS), and total hospital charges.
METHODS
The population consisted of 417,301 adult hospitalizations from January 1, 2009 to August 31, 2011, in an academic medical center and 9 community hospitals. Patients with anemia on admission, and hospitals in the health system without available laboratory data were excluded; 188,447 hospitalizations were included in the analysis. Demographics, comorbidities, and outcomes were retrieved from administrative data; Hgb values were taken from the electronic medical record. Regression modeling was used to examine the association between demographics, comorbidity, hospitalization type, and HAA variables (mild: Hgb >11 and <12 g/dL for women, and >11 and <13 g/dL for men; moderate: Hgb 9.1 to ≤11.0 g/dL; severe: Hgb ≤9.0 g/dL) on mortality, LOS, and hospital charges.
RESULTS
Among 188,447 hospitalizations, 139,807 patients (74%) developed HAA: mild, 40,828 (29%); moderate, 57,184 (41%); and severe, 41,795 (30%). Risk‐adjusted odds ratios and 95% confidence intervals for in‐hospital mortality with HAA were: mild, 1.0 (0.88–1.17; P = 0.8); moderate, 1.51 (1.33–1.71, P < 0.001); and severe, 3.28 (2.90–3.72, P < 0.001). Risk–adjusted relative mean LOS and hospital charges relative to no HAA were higher with HAA: LOS: mild, 1.08 (1.08–1.10, P < 0.001); moderate, 1.28 (1.26–1.29, P < 0.001); severe, 1.88 (1.86–1.89, P < 0.001). Hospital charges: mild, 1.06 (1.06–1.07, P < 0.001); moderate, 1.18 (1.17–1.19, P < 0.001); severe, 1.80 (1.79–1.82, P < 0.001).
CONCLUSIONS
HAA is common and associated with increased mortality and resource utilization. Factors related to its development necessitate further study. Journal of Hospital Medicine 2013;8:506–512. © 2013 Society of Hospital Medicine]]></description><identifier>ISSN: 1553-5592</identifier><identifier>EISSN: 1553-5606</identifier><identifier>DOI: 10.1002/jhm.2061</identifier><identifier>PMID: 23873739</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Anemia ; Anemia - diagnosis ; Anemia - mortality ; Confidence intervals ; Female ; Hospital Charges - trends ; Hospital Mortality - trends ; Hospitalization ; Hospitalization - trends ; Hospitals ; Humans ; Length of Stay - trends ; Male ; Middle Aged ; Mortality ; Prevalence ; Quality of Health Care - trends ; Treatment Outcome</subject><ispartof>Journal of hospital medicine, 2013-09, Vol.8 (9), p.506-512</ispartof><rights>Copyright © 2013 Society of Hospital Medicine</rights><rights>Copyright © 2013 Society of Hospital Medicine.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4211-4352a14b98f8486fa48217690251284565778e378e1f93ba4818ad8cdbf35af3</citedby><cites>FETCH-LOGICAL-c4211-4352a14b98f8486fa48217690251284565778e378e1f93ba4818ad8cdbf35af3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjhm.2061$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjhm.2061$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23873739$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Koch, Colleen G.</creatorcontrib><creatorcontrib>Li, Liang</creatorcontrib><creatorcontrib>Sun, Zhiyuan</creatorcontrib><creatorcontrib>Hixson, Eric D.</creatorcontrib><creatorcontrib>Tang, Anne</creatorcontrib><creatorcontrib>Phillips, Shannon C.</creatorcontrib><creatorcontrib>Blackstone, Eugene H.</creatorcontrib><creatorcontrib>Henderson, J. Michael</creatorcontrib><title>Hospital-acquired anemia: Prevalence, outcomes, and healthcare implications</title><title>Journal of hospital medicine</title><addtitle>J. Hosp. Med</addtitle><description><![CDATA[BACKGROUND
Evidence suggests that patients with normal hemoglobin (Hgb) levels on hospital admission who subsequently develop hospital‐acquired anemia (HAA) may be at risk for adverse outcomes. Our objectives were to (1) determine the prevalence of HAA and (2) examine whether HAA is associated with increased mortality, length of stay (LOS), and total hospital charges.
METHODS
The population consisted of 417,301 adult hospitalizations from January 1, 2009 to August 31, 2011, in an academic medical center and 9 community hospitals. Patients with anemia on admission, and hospitals in the health system without available laboratory data were excluded; 188,447 hospitalizations were included in the analysis. Demographics, comorbidities, and outcomes were retrieved from administrative data; Hgb values were taken from the electronic medical record. Regression modeling was used to examine the association between demographics, comorbidity, hospitalization type, and HAA variables (mild: Hgb >11 and <12 g/dL for women, and >11 and <13 g/dL for men; moderate: Hgb 9.1 to ≤11.0 g/dL; severe: Hgb ≤9.0 g/dL) on mortality, LOS, and hospital charges.
RESULTS
Among 188,447 hospitalizations, 139,807 patients (74%) developed HAA: mild, 40,828 (29%); moderate, 57,184 (41%); and severe, 41,795 (30%). Risk‐adjusted odds ratios and 95% confidence intervals for in‐hospital mortality with HAA were: mild, 1.0 (0.88–1.17; P = 0.8); moderate, 1.51 (1.33–1.71, P < 0.001); and severe, 3.28 (2.90–3.72, P < 0.001). Risk–adjusted relative mean LOS and hospital charges relative to no HAA were higher with HAA: LOS: mild, 1.08 (1.08–1.10, P < 0.001); moderate, 1.28 (1.26–1.29, P < 0.001); severe, 1.88 (1.86–1.89, P < 0.001). Hospital charges: mild, 1.06 (1.06–1.07, P < 0.001); moderate, 1.18 (1.17–1.19, P < 0.001); severe, 1.80 (1.79–1.82, P < 0.001).
CONCLUSIONS
HAA is common and associated with increased mortality and resource utilization. Factors related to its development necessitate further study. Journal of Hospital Medicine 2013;8:506–512. © 2013 Society of Hospital Medicine]]></description><subject>Adult</subject><subject>Aged</subject><subject>Anemia</subject><subject>Anemia - diagnosis</subject><subject>Anemia - mortality</subject><subject>Confidence intervals</subject><subject>Female</subject><subject>Hospital Charges - trends</subject><subject>Hospital Mortality - trends</subject><subject>Hospitalization</subject><subject>Hospitalization - trends</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Length of Stay - trends</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Prevalence</subject><subject>Quality of Health Care - trends</subject><subject>Treatment Outcome</subject><issn>1553-5592</issn><issn>1553-5606</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kF1LwzAUhoMobk7BXyAFb7xYNZ9t4p3Mj6lTdzH0MmRpyjLbdUtadf_eDLcJgheHc-B9eDi8ABwjeI4gxBfTSXmOYYJ2QBsxRmKWwGR3czOBW-DA-ymElHBG90ELE56SlIg2eOxXfm5rVcRKLxrrTBapmSmtuoyGznyowsy06UZVU-uqNL4b0iyaGFXUE62ciWw5L6xWta1m_hDs5arw5mi9O2B0ezPq9ePBy91972oQa4oRiilhWCE6FjznlCe5ohyjNBEQM4Q5ZQlLU25IGJQLMg4x4irjOhvnhKmcdMDZj3buqkVjfC1L67UpivB41XiJKCE4xQKSgJ7-QadV42bhuRUFSQK5SH-F2lXeO5PLubOlckuJoFz1K0O_ctVvQE_WwmZcmmwLbgoNQPwDfNrCLP8VyYf-01q45q2vzdeWV-5dJsHI5NvznXx6RQwNr4UU5BvvXpCW</recordid><startdate>201309</startdate><enddate>201309</enddate><creator>Koch, Colleen G.</creator><creator>Li, Liang</creator><creator>Sun, Zhiyuan</creator><creator>Hixson, Eric D.</creator><creator>Tang, Anne</creator><creator>Phillips, Shannon C.</creator><creator>Blackstone, Eugene H.</creator><creator>Henderson, J. Michael</creator><general>Blackwell Publishing Ltd</general><general>Frontline Medical Communications</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201309</creationdate><title>Hospital-acquired anemia: Prevalence, outcomes, and healthcare implications</title><author>Koch, Colleen G. ; Li, Liang ; Sun, Zhiyuan ; Hixson, Eric D. ; Tang, Anne ; Phillips, Shannon C. ; Blackstone, Eugene H. ; Henderson, J. Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4211-4352a14b98f8486fa48217690251284565778e378e1f93ba4818ad8cdbf35af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Anemia</topic><topic>Anemia - diagnosis</topic><topic>Anemia - mortality</topic><topic>Confidence intervals</topic><topic>Female</topic><topic>Hospital Charges - trends</topic><topic>Hospital Mortality - trends</topic><topic>Hospitalization</topic><topic>Hospitalization - trends</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Length of Stay - trends</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Prevalence</topic><topic>Quality of Health Care - trends</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Koch, Colleen G.</creatorcontrib><creatorcontrib>Li, Liang</creatorcontrib><creatorcontrib>Sun, Zhiyuan</creatorcontrib><creatorcontrib>Hixson, Eric D.</creatorcontrib><creatorcontrib>Tang, Anne</creatorcontrib><creatorcontrib>Phillips, Shannon C.</creatorcontrib><creatorcontrib>Blackstone, Eugene H.</creatorcontrib><creatorcontrib>Henderson, J. Michael</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of hospital medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Koch, Colleen G.</au><au>Li, Liang</au><au>Sun, Zhiyuan</au><au>Hixson, Eric D.</au><au>Tang, Anne</au><au>Phillips, Shannon C.</au><au>Blackstone, Eugene H.</au><au>Henderson, J. Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hospital-acquired anemia: Prevalence, outcomes, and healthcare implications</atitle><jtitle>Journal of hospital medicine</jtitle><addtitle>J. Hosp. Med</addtitle><date>2013-09</date><risdate>2013</risdate><volume>8</volume><issue>9</issue><spage>506</spage><epage>512</epage><pages>506-512</pages><issn>1553-5592</issn><eissn>1553-5606</eissn><abstract><![CDATA[BACKGROUND
Evidence suggests that patients with normal hemoglobin (Hgb) levels on hospital admission who subsequently develop hospital‐acquired anemia (HAA) may be at risk for adverse outcomes. Our objectives were to (1) determine the prevalence of HAA and (2) examine whether HAA is associated with increased mortality, length of stay (LOS), and total hospital charges.
METHODS
The population consisted of 417,301 adult hospitalizations from January 1, 2009 to August 31, 2011, in an academic medical center and 9 community hospitals. Patients with anemia on admission, and hospitals in the health system without available laboratory data were excluded; 188,447 hospitalizations were included in the analysis. Demographics, comorbidities, and outcomes were retrieved from administrative data; Hgb values were taken from the electronic medical record. Regression modeling was used to examine the association between demographics, comorbidity, hospitalization type, and HAA variables (mild: Hgb >11 and <12 g/dL for women, and >11 and <13 g/dL for men; moderate: Hgb 9.1 to ≤11.0 g/dL; severe: Hgb ≤9.0 g/dL) on mortality, LOS, and hospital charges.
RESULTS
Among 188,447 hospitalizations, 139,807 patients (74%) developed HAA: mild, 40,828 (29%); moderate, 57,184 (41%); and severe, 41,795 (30%). Risk‐adjusted odds ratios and 95% confidence intervals for in‐hospital mortality with HAA were: mild, 1.0 (0.88–1.17; P = 0.8); moderate, 1.51 (1.33–1.71, P < 0.001); and severe, 3.28 (2.90–3.72, P < 0.001). Risk–adjusted relative mean LOS and hospital charges relative to no HAA were higher with HAA: LOS: mild, 1.08 (1.08–1.10, P < 0.001); moderate, 1.28 (1.26–1.29, P < 0.001); severe, 1.88 (1.86–1.89, P < 0.001). Hospital charges: mild, 1.06 (1.06–1.07, P < 0.001); moderate, 1.18 (1.17–1.19, P < 0.001); severe, 1.80 (1.79–1.82, P < 0.001).
CONCLUSIONS
HAA is common and associated with increased mortality and resource utilization. Factors related to its development necessitate further study. Journal of Hospital Medicine 2013;8:506–512. © 2013 Society of Hospital Medicine]]></abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>23873739</pmid><doi>10.1002/jhm.2061</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1553-5592 |
| ispartof | Journal of hospital medicine, 2013-09, Vol.8 (9), p.506-512 |
| issn | 1553-5592 1553-5606 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1433272903 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Anemia Anemia - diagnosis Anemia - mortality Confidence intervals Female Hospital Charges - trends Hospital Mortality - trends Hospitalization Hospitalization - trends Hospitals Humans Length of Stay - trends Male Middle Aged Mortality Prevalence Quality of Health Care - trends Treatment Outcome |
| title | Hospital-acquired anemia: Prevalence, outcomes, and healthcare implications |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T09%3A52%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hospital-acquired%20anemia:%20Prevalence,%20outcomes,%20and%20healthcare%20implications&rft.jtitle=Journal%20of%20hospital%20medicine&rft.au=Koch,%20Colleen%20G.&rft.date=2013-09&rft.volume=8&rft.issue=9&rft.spage=506&rft.epage=512&rft.pages=506-512&rft.issn=1553-5592&rft.eissn=1553-5606&rft_id=info:doi/10.1002/jhm.2061&rft_dat=%3Cproquest_cross%3E3063884411%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1430360897&rft_id=info:pmid/23873739&rfr_iscdi=true |