Mouse major histocompatibility class I gene expression begins at midsomite stage and is inducible in earlier-stage embryos by interferon

To determine the timing of major histocompatibility complex class I gene expression during embryonic development, binding of anti-class I antibodies and appearance of class I gene transcripts were examined in mouse embryos from the egg-cylinder stage through day 16 of gestation. By using two series...

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Veröffentlicht in:	Proc. Natl. Acad. Sci. U.S.A.; (United States) 1985-04, Vol.82 (8), p.2427-2431
Hauptverfasser:	Ozato, K, Wan, Y.J, Orrison, B.M
Format:	Artikel
Sprache:	eng
Schlagworte:	550601 - Medicine- Unsealed Radionuclides in Diagnostics ANIMALS ANTIBODIES ANTIGENE ANTIGENOS ANTIGENS BETA DECAY RADIOISOTOPES BIOCHEMISTRY CHEMICAL ACTIVATION CHEMISTRY DAYS LIVING RADIOISOTOPES DESARROLLO EMBRIONARIO DEVELOPPEMENT EMBRYONNAIRE ELECTRON CAPTURE RADIOISOTOPES Embryo, Mammalian - immunology Embryonic cells EMBRYONIC DEVELOPMENT EMBRYOS GENE EXPRESSION Gene Expression Regulation - drug effects GENES Germ cells Gestational Age H-2 Antigens - genetics HISTOCOMPATIBILIDAD HISTOCOMPATIBILITE HISTOCOMPATIBILITY Histocompatibility antigens class I IMMUNE RESPONSE IMMUNOLOGY INTERFERON Interferons - pharmacology INTERMEDIATE MASS NUCLEI IODINE 125 IODINE ISOTOPES ISOTOPE APPLICATIONS ISOTOPES LYMPHOKINES MAMMALS Messenger RNA MHC class I genes MICE Mice, Inbred Strains MONOCLONAL ANTIBODIES NUCLEI ODD-EVEN NUCLEI ONTOGENESIS Pregnancy RADIOASSAY RADIOIMMUNOASSAY RADIOIMMUNOLOGY RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE RATON REPONSE IMMUNITAIRE RESPUESTA INMUNOLOGICA RNA RNA, Messenger - genetics RNA, Messenger - metabolism RODENTS SOURIS TRACER TECHNIQUES VERTEBRATES
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