Resuscitation from experimental traumatic brain injury by magnolol therapy

Abstract Background The purpose of the present study was to determine whether magnolol, a free radical scavenger, mitigates the deleterious effects of traumatic brain injury (TBI). Material and methods Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percuss...

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Veröffentlicht in:	The Journal of surgical research 2013-10, Vol.184 (2), p.1045-1052
Hauptverfasser:	Wang, Che-Chuan, MD, Lin, Kao-Chang, MD, Lin, Bor-Shyh, PhD, Chio, Chung-Ching, MD, Kuo, Jinn-Rung, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biphenyl Compounds - therapeutic use Brain Injuries - drug therapy Disease Models, Animal Free radical scavenger Free Radical Scavengers - therapeutic use Glycerol - metabolism Hippocampus - metabolism Hippocampus - pathology Hydroxybenzoates - metabolism Lignans - therapeutic use Magnolol Male Models, Animal Neuronal apoptosis Neuroprotective Agents - therapeutic use Rats Rats, Sprague-Dawley Resuscitation - methods Surgery Transforming Growth Factor beta1 - metabolism Transforming growth factor β1 Traumatic brain injury
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