Circulating immune complexes in asbestos workers
Circulating immune complexes, rheumatoid factor, and antinuclear antibodies were evaluated in 25 asbestos insulation workers and 32 brick mason controls. There were 10 asbestos workers with radiographic parenchymal or pleural changes, consistent with their asbestos exposure. There were no difference...
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Veröffentlicht in: | Environ. Res.; (United States) 1985-08, Vol.37 (2), p.383-389 |
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description | Circulating immune complexes, rheumatoid factor, and antinuclear antibodies were evaluated in 25 asbestos insulation workers and 32 brick mason controls. There were 10 asbestos workers with radiographic parenchymal or pleural changes, consistent with their asbestos exposure. There were no differences in antinuclear antibodies or rheumatoid factor between asbestos workers and controls. The asbestos workers had significantly increased levels of IgG and IgA circulating immune complexes. There was a significant correlation between IgA circulating immune complexes and radiographic changes. |
doi_str_mv | 10.1016/0013-9351(85)90119-7 |
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There were 10 asbestos workers with radiographic parenchymal or pleural changes, consistent with their asbestos exposure. There were no differences in antinuclear antibodies or rheumatoid factor between asbestos workers and controls. The asbestos workers had significantly increased levels of IgG and IgA circulating immune complexes. There was a significant correlation between IgA circulating immune complexes and radiographic changes.</description><identifier>ISSN: 0013-9351</identifier><identifier>EISSN: 1096-0953</identifier><identifier>DOI: 10.1016/0013-9351(85)90119-7</identifier><identifier>PMID: 3874772</identifier><identifier>CODEN: ENVRAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>560306 - Chemicals Metabolism & Toxicology- Man- (-1987) ; Adult ; Aged ; Antibodies, Antinuclear - analysis ; Antibodies, Antinuclear - immunology ; Antigen-Antibody Complex - immunology ; ASBESTOS ; Asbestos - immunology ; Biological and medical sciences ; BIOLOGICAL EFFECTS ; Chemical and industrial products toxicology. Toxic occupational diseases ; Environmental Exposure ; Female ; GLOBULINS ; Humans ; Immunoglobulin A - analysis ; Immunoglobulin A - immunology ; Immunoglobulin G - analysis ; Immunoglobulin G - immunology ; IMMUNOGLOBULINS ; IMMUNOLOGY ; Inorganic dusts (pneumoconiosises) and organic dusts (byssinosis etc.) ; IODINE ISOTOPES ; ISOTOPE APPLICATIONS ; ISOTOPES ; Lung - diagnostic imaging ; Male ; Maximal Expiratory Flow Rate ; Medical sciences ; Middle Aged ; OCCUPATIONAL EXPOSURE ; ORGANIC COMPOUNDS ; PROTEINS ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT ; RADIOASSAY ; Radiography ; RADIOIMMUNOASSAY ; RADIOIMMUNOLOGY ; Rheumatoid Factor - analysis ; Rheumatoid Factor - immunology ; Spirometry ; Toxicology ; TRACER TECHNIQUES ; Vital Capacity</subject><ispartof>Environ. Res.; (United States), 1985-08, Vol.37 (2), p.383-389</ispartof><rights>1985</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-89172897b36b09c870cd2c694696044680c3f634ced01b3c5d2aa122f754f7383</citedby><cites>FETCH-LOGICAL-c475t-89172897b36b09c870cd2c694696044680c3f634ced01b3c5d2aa122f754f7383</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0013935185901197$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8508705$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3874772$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6330547$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Zone, John J.</creatorcontrib><creatorcontrib>Rom, William N.</creatorcontrib><creatorcontrib>Univ. of Utah School of Medicine, Salt Lake City</creatorcontrib><title>Circulating immune complexes in asbestos workers</title><title>Environ. Res.; (United States)</title><addtitle>Environ Res</addtitle><description>Circulating immune complexes, rheumatoid factor, and antinuclear antibodies were evaluated in 25 asbestos insulation workers and 32 brick mason controls. There were 10 asbestos workers with radiographic parenchymal or pleural changes, consistent with their asbestos exposure. There were no differences in antinuclear antibodies or rheumatoid factor between asbestos workers and controls. The asbestos workers had significantly increased levels of IgG and IgA circulating immune complexes. There was a significant correlation between IgA circulating immune complexes and radiographic changes.</description><subject>560306 - Chemicals Metabolism & Toxicology- Man- (-1987)</subject><subject>Adult</subject><subject>Aged</subject><subject>Antibodies, Antinuclear - analysis</subject><subject>Antibodies, Antinuclear - immunology</subject><subject>Antigen-Antibody Complex - immunology</subject><subject>ASBESTOS</subject><subject>Asbestos - immunology</subject><subject>Biological and medical sciences</subject><subject>BIOLOGICAL EFFECTS</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Environmental Exposure</subject><subject>Female</subject><subject>GLOBULINS</subject><subject>Humans</subject><subject>Immunoglobulin A - analysis</subject><subject>Immunoglobulin A - immunology</subject><subject>Immunoglobulin G - analysis</subject><subject>Immunoglobulin G - immunology</subject><subject>IMMUNOGLOBULINS</subject><subject>IMMUNOLOGY</subject><subject>Inorganic dusts (pneumoconiosises) and organic dusts (byssinosis etc.)</subject><subject>IODINE ISOTOPES</subject><subject>ISOTOPE APPLICATIONS</subject><subject>ISOTOPES</subject><subject>Lung - diagnostic imaging</subject><subject>Male</subject><subject>Maximal Expiratory Flow Rate</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>OCCUPATIONAL EXPOSURE</subject><subject>ORGANIC COMPOUNDS</subject><subject>PROTEINS</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</subject><subject>RADIOASSAY</subject><subject>Radiography</subject><subject>RADIOIMMUNOASSAY</subject><subject>RADIOIMMUNOLOGY</subject><subject>Rheumatoid Factor - analysis</subject><subject>Rheumatoid Factor - immunology</subject><subject>Spirometry</subject><subject>Toxicology</subject><subject>TRACER TECHNIQUES</subject><subject>Vital Capacity</subject><issn>0013-9351</issn><issn>1096-0953</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1v1DAQhi0EKtvCP2ilCFUIDgFP_H2pVK3Kh1SJSzlbzsQBlyRe7ATov8fprvaIOFnWPPPqnYeQc6DvgIJ8Tymw2jABb7R4ayiAqdUTsgFqZE2NYE_J5og8J6c535cvCEZPyAnTiivVbAjdhoTL4OYwfavCOC6TrzCOu8H_8bkKU-Vy6_Mcc_U7ph8-5RfkWe-G7F8e3jPy9cPN3fZTffvl4-ft9W2NXIm51gZUo41qmWypQa0odg1Kw6WRlHOpKbJeMo6-o9AyFF3jHDRNrwTvFdPsjLza58Y8B5sxzB6_Y5wmj7OVjFHBVYFe76Fdij-X0tOOIaMfBjf5uGQLnDUcFPwHCKWXWRP5HsQUc06-t7sURpceLFC7arerU7s6tVrYR-12Xbs45C_t6Lvj0sFzmV8e5i6jG_rkJgz5iGlBiyFRsKs95ovZX8Gn9XA_FUkhrXd3Mfy7x1-k0JsS</recordid><startdate>198508</startdate><enddate>198508</enddate><creator>Zone, John J.</creator><creator>Rom, William N.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>7T2</scope><scope>7T5</scope><scope>7TV</scope><scope>7U2</scope><scope>7U7</scope><scope>H94</scope><scope>OTOTI</scope></search><sort><creationdate>198508</creationdate><title>Circulating immune complexes in asbestos workers</title><author>Zone, John J. ; Rom, William N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-89172897b36b09c870cd2c694696044680c3f634ced01b3c5d2aa122f754f7383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>560306 - Chemicals Metabolism & Toxicology- Man- (-1987)</topic><topic>Adult</topic><topic>Aged</topic><topic>Antibodies, Antinuclear - analysis</topic><topic>Antibodies, Antinuclear - immunology</topic><topic>Antigen-Antibody Complex - immunology</topic><topic>ASBESTOS</topic><topic>Asbestos - immunology</topic><topic>Biological and medical sciences</topic><topic>BIOLOGICAL EFFECTS</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Environmental Exposure</topic><topic>Female</topic><topic>GLOBULINS</topic><topic>Humans</topic><topic>Immunoglobulin A - analysis</topic><topic>Immunoglobulin A - immunology</topic><topic>Immunoglobulin G - analysis</topic><topic>Immunoglobulin G - immunology</topic><topic>IMMUNOGLOBULINS</topic><topic>IMMUNOLOGY</topic><topic>Inorganic dusts (pneumoconiosises) and organic dusts (byssinosis etc.)</topic><topic>IODINE ISOTOPES</topic><topic>ISOTOPE APPLICATIONS</topic><topic>ISOTOPES</topic><topic>Lung - diagnostic imaging</topic><topic>Male</topic><topic>Maximal Expiratory Flow Rate</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>OCCUPATIONAL EXPOSURE</topic><topic>ORGANIC COMPOUNDS</topic><topic>PROTEINS</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</topic><topic>RADIOASSAY</topic><topic>Radiography</topic><topic>RADIOIMMUNOASSAY</topic><topic>RADIOIMMUNOLOGY</topic><topic>Rheumatoid Factor - analysis</topic><topic>Rheumatoid Factor - immunology</topic><topic>Spirometry</topic><topic>Toxicology</topic><topic>TRACER TECHNIQUES</topic><topic>Vital Capacity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zone, John J.</creatorcontrib><creatorcontrib>Rom, William N.</creatorcontrib><creatorcontrib>Univ. of Utah School of Medicine, Salt Lake City</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Pollution Abstracts</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>OSTI.GOV</collection><jtitle>Environ. Res.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zone, John J.</au><au>Rom, William N.</au><aucorp>Univ. of Utah School of Medicine, Salt Lake City</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Circulating immune complexes in asbestos workers</atitle><jtitle>Environ. Res.; (United States)</jtitle><addtitle>Environ Res</addtitle><date>1985-08</date><risdate>1985</risdate><volume>37</volume><issue>2</issue><spage>383</spage><epage>389</epage><pages>383-389</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><coden>ENVRAL</coden><abstract>Circulating immune complexes, rheumatoid factor, and antinuclear antibodies were evaluated in 25 asbestos insulation workers and 32 brick mason controls. There were 10 asbestos workers with radiographic parenchymal or pleural changes, consistent with their asbestos exposure. There were no differences in antinuclear antibodies or rheumatoid factor between asbestos workers and controls. The asbestos workers had significantly increased levels of IgG and IgA circulating immune complexes. There was a significant correlation between IgA circulating immune complexes and radiographic changes.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>3874772</pmid><doi>10.1016/0013-9351(85)90119-7</doi><tpages>7</tpages></addata></record> |
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subjects | 560306 - Chemicals Metabolism & Toxicology- Man- (-1987) Adult Aged Antibodies, Antinuclear - analysis Antibodies, Antinuclear - immunology Antigen-Antibody Complex - immunology ASBESTOS Asbestos - immunology Biological and medical sciences BIOLOGICAL EFFECTS Chemical and industrial products toxicology. Toxic occupational diseases Environmental Exposure Female GLOBULINS Humans Immunoglobulin A - analysis Immunoglobulin A - immunology Immunoglobulin G - analysis Immunoglobulin G - immunology IMMUNOGLOBULINS IMMUNOLOGY Inorganic dusts (pneumoconiosises) and organic dusts (byssinosis etc.) IODINE ISOTOPES ISOTOPE APPLICATIONS ISOTOPES Lung - diagnostic imaging Male Maximal Expiratory Flow Rate Medical sciences Middle Aged OCCUPATIONAL EXPOSURE ORGANIC COMPOUNDS PROTEINS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOASSAY Radiography RADIOIMMUNOASSAY RADIOIMMUNOLOGY Rheumatoid Factor - analysis Rheumatoid Factor - immunology Spirometry Toxicology TRACER TECHNIQUES Vital Capacity |
title | Circulating immune complexes in asbestos workers |
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