A novel biomarker panel to rule out acute appendicitis in pediatric patients with abdominal pain

Abstract Objectives To identify a biomarker panel with sufficient sensitivity and negative predictive value to identify children with abdominal pain at low risk for acute appendicitis in order to avoid unnecessary imaging. Methods We prospectively enrolled 503 subjects aged two to 20 years with <...

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Veröffentlicht in:	The American journal of emergency medicine 2013-09, Vol.31 (9), p.1368-1375
Hauptverfasser:	Huckins, David S., MD, Simon, Harold K., MD, Copeland, Karen, PhD, Spiro, David M., MD, Gogain, Joseph, PhD, Wandell, Michael, PharmD
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Abdominal Pain - blood Abdominal Pain - diagnosis Accuracy Adolescent Appendicitis Appendicitis - blood Appendicitis - diagnosis Appendicitis - diagnostic imaging Biomarkers Biomarkers - blood Blood Blood Cell Count C-Reactive Protein - analysis Calgranulin A - blood Calgranulin B - blood Child Child, Preschool Consent Emergency Emergency medical care Female Humans Ionizing radiation Leukocyte Count Male Medical imaging Pain Pediatrics Plasma Predictive Value of Tests Prospective Studies Proteins Review boards Risk Factors Sensitivity and Specificity Surgery Testing laboratories Tomography, X-Ray Computed Young Adult
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