TXA2 synthesis and COX1-independent platelet reactivity in aspirin-treated patients soon after acute cerebral stroke or transient ischaemic attack

Abstract Introduction The pharmacological target of aspirin is the inhibition of cyclooxygenase-1 (COX1) and thromboxane-A2 (TX) synthesis. Very few data are available on TX assessment in patients with stroke. We studied platelet TX synthesis, COX1-independent platelet reactivity, the influence of p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Thrombosis research 2013-08, Vol.132 (2), p.211-216
Hauptverfasser:	Valles, Juana, Lago, Aida, Moscardo, Antonio, I.Tembl, Jose, Parkhutik, Vera, Santos, Maria T
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Acute stroke Aged Aspirin Aspirin - therapeutic use Case-Control Studies Cyclooxygenase 1 - biosynthesis Cyclooxygenase 1 - blood Cyclooxygenase Inhibitors - therapeutic use Cyclooxygenase-1 Female Hematology, Oncology and Palliative Medicine Humans Ischemic Attack, Transient - blood Ischemic Attack, Transient - drug therapy Ischemic Attack, Transient - enzymology Male Platelet Aggregation - drug effects Platelet–erythrocyte interactions Stroke - blood Stroke - drug therapy Stroke - enzymology Thromboxane A2 Thromboxane A2 - biosynthesis Thromboxane A2 - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!