Drug interactions in Brazilian type 2 diabetes patients
The aim of this paper is to identify the prevalence of the most frequent drug interactions in patients using oral antidiabéticos and their association with capillary glucose and medication adherence. In total, 579 type 2 diabetes mellitus patients from 12 health institutions in Fortaleza, Brazil wer...
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| Veröffentlicht in: | International journal of nursing practice 2013-08, Vol.19 (4), p.423-430 |
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| container_title | International journal of nursing practice |
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| creator | de Araújo, Márcio Flávio Moura dos Santos Alves, Priscila de Jesus Veras, Vivian Saraiva de Araújo, Thiago Moura Zanetti, Maria Lúcia Damasceno, Marta Maria Coelho |
| description | The aim of this paper is to identify the prevalence of the most frequent drug interactions in patients using oral antidiabéticos and their association with capillary glucose and medication adherence. In total, 579 type 2 diabetes mellitus patients from 12 health institutions in Fortaleza, Brazil were interviewed in 2009. A form was applied, including questions on medication use, comorbidities, lifestyle, body mass index and random capillary glucose. Results revealed that 26.7% used five or more different drugs simultaneously and daily. Statistically significant drug interactions occurred between antidiabéticos and diuretics, angiotensin‐converting enzyme inhibitors, anti‐lipidaemics and corticoids. No significant association was found between polypharmacy, medication adherence and glucose. It is important for nurses, in consensus with other health professionals, to consider the possibility of other drugs that mean less risk for diabetes patients’ glucose control or of increased antidiabetics doses. |
| doi_str_mv | 10.1111/ijn.12078 |
| format | Article |
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In total, 579 type 2 diabetes mellitus patients from 12 health institutions in Fortaleza, Brazil were interviewed in 2009. A form was applied, including questions on medication use, comorbidities, lifestyle, body mass index and random capillary glucose. Results revealed that 26.7% used five or more different drugs simultaneously and daily. Statistically significant drug interactions occurred between antidiabéticos and diuretics, angiotensin‐converting enzyme inhibitors, anti‐lipidaemics and corticoids. No significant association was found between polypharmacy, medication adherence and glucose. It is important for nurses, in consensus with other health professionals, to consider the possibility of other drugs that mean less risk for diabetes patients’ glucose control or of increased antidiabetics doses.</description><identifier>ISSN: 1322-7114</identifier><identifier>EISSN: 1440-172X</identifier><identifier>DOI: 10.1111/ijn.12078</identifier><identifier>PMID: 23915412</identifier><language>eng</language><publisher>Australia: Blackwell Publishing Ltd</publisher><subject>Adherence ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; antihypertensives ; Brazil ; Comorbidity ; Cross-Sectional Studies ; Diabetes ; Diabetes Mellitus, Type 2 - drug therapy ; Diabetics ; Drug Interactions ; Drugs ; Female ; Glucose ; Humans ; hypoglycaemics ; Hypoglycemic Agents - pharmacology ; Hypoglycemic Agents - therapeutic use ; Male ; Middle Aged ; Nursing ; Patient Compliance ; Patients ; Pharmacology ; Prevalence ; Type 2 diabetes mellitus</subject><ispartof>International journal of nursing practice, 2013-08, Vol.19 (4), p.423-430</ispartof><rights>2013 Wiley Publishing Asia Pty Ltd</rights><rights>2013 Wiley Publishing Asia Pty Ltd.</rights><rights>Copyright Blackwell Publishing Ltd. Aug 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fijn.12078$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fijn.12078$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,30976,30977,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23915412$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Araújo, Márcio Flávio Moura</creatorcontrib><creatorcontrib>dos Santos Alves, Priscila de Jesus</creatorcontrib><creatorcontrib>Veras, Vivian Saraiva</creatorcontrib><creatorcontrib>de Araújo, Thiago Moura</creatorcontrib><creatorcontrib>Zanetti, Maria Lúcia</creatorcontrib><creatorcontrib>Damasceno, Marta Maria Coelho</creatorcontrib><title>Drug interactions in Brazilian type 2 diabetes patients</title><title>International journal of nursing practice</title><addtitle>Int J Nurs Pract</addtitle><description>The aim of this paper is to identify the prevalence of the most frequent drug interactions in patients using oral antidiabéticos and their association with capillary glucose and medication adherence. In total, 579 type 2 diabetes mellitus patients from 12 health institutions in Fortaleza, Brazil were interviewed in 2009. A form was applied, including questions on medication use, comorbidities, lifestyle, body mass index and random capillary glucose. Results revealed that 26.7% used five or more different drugs simultaneously and daily. Statistically significant drug interactions occurred between antidiabéticos and diuretics, angiotensin‐converting enzyme inhibitors, anti‐lipidaemics and corticoids. No significant association was found between polypharmacy, medication adherence and glucose. It is important for nurses, in consensus with other health professionals, to consider the possibility of other drugs that mean less risk for diabetes patients’ glucose control or of increased antidiabetics doses.</description><subject>Adherence</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>antihypertensives</subject><subject>Brazil</subject><subject>Comorbidity</subject><subject>Cross-Sectional Studies</subject><subject>Diabetes</subject><subject>Diabetes Mellitus, Type 2 - drug therapy</subject><subject>Diabetics</subject><subject>Drug Interactions</subject><subject>Drugs</subject><subject>Female</subject><subject>Glucose</subject><subject>Humans</subject><subject>hypoglycaemics</subject><subject>Hypoglycemic Agents - pharmacology</subject><subject>Hypoglycemic Agents - therapeutic use</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nursing</subject><subject>Patient Compliance</subject><subject>Patients</subject><subject>Pharmacology</subject><subject>Prevalence</subject><subject>Type 2 diabetes mellitus</subject><issn>1322-7114</issn><issn>1440-172X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqNkU1P5DAMhiME4vuwfwBV4rKXgu2kSXtcWL6_hACB9hJlWoMy2-kMTSsYfj2BAQ6c8CV2_Ly2kleIXwhbGGPbD5stJDD5nFhGpSBFQ3fzMZdEqUFUS2IlhCFAvMBsUSyRLDBTSMvC_G37h8Q3Hbeu7Py4CbFIdlr34mvvmqSbTjihpPJuwB2HZOI6z00X1sTCvasDr3-cq-Jmf-969zA9vTg42v1zmnqFeZ5melAyIJcKNGmN4JyqXH4PRMYVA11kKmddGKIyM4wZYZUrIEmaJRuq5Kr4PZs7acePPYfOjnwoua5dw-M-WFQSAQrS8icoYF6Axh-gmEttQENEN7-hw3HfNvHNkSKVSZTF2-6ND6ofjLiyk9aPXDu1nx8dge0Z8ORrnn71EeybgzY6aN8dtEfH5-9JVKQzhQ8dP38pXPvfaiNNZm_PD-y_S7N_dbJzZq_kK3EvmBU</recordid><startdate>201308</startdate><enddate>201308</enddate><creator>de Araújo, Márcio Flávio Moura</creator><creator>dos Santos Alves, Priscila de Jesus</creator><creator>Veras, Vivian Saraiva</creator><creator>de Araújo, Thiago Moura</creator><creator>Zanetti, Maria Lúcia</creator><creator>Damasceno, Marta Maria Coelho</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QJ</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201308</creationdate><title>Drug interactions in Brazilian type 2 diabetes patients</title><author>de Araújo, Márcio Flávio Moura ; dos Santos Alves, Priscila de Jesus ; Veras, Vivian Saraiva ; de Araújo, Thiago Moura ; Zanetti, Maria Lúcia ; Damasceno, Marta Maria Coelho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i4188-56bce01ec40626610aa4da8f0227a9b69548e69722c57e1521d8402326e3e72d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adherence</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>antihypertensives</topic><topic>Brazil</topic><topic>Comorbidity</topic><topic>Cross-Sectional Studies</topic><topic>Diabetes</topic><topic>Diabetes Mellitus, Type 2 - drug therapy</topic><topic>Diabetics</topic><topic>Drug Interactions</topic><topic>Drugs</topic><topic>Female</topic><topic>Glucose</topic><topic>Humans</topic><topic>hypoglycaemics</topic><topic>Hypoglycemic Agents - pharmacology</topic><topic>Hypoglycemic Agents - therapeutic use</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nursing</topic><topic>Patient Compliance</topic><topic>Patients</topic><topic>Pharmacology</topic><topic>Prevalence</topic><topic>Type 2 diabetes mellitus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Araújo, Márcio Flávio Moura</creatorcontrib><creatorcontrib>dos Santos Alves, Priscila de Jesus</creatorcontrib><creatorcontrib>Veras, Vivian Saraiva</creatorcontrib><creatorcontrib>de Araújo, Thiago Moura</creatorcontrib><creatorcontrib>Zanetti, Maria Lúcia</creatorcontrib><creatorcontrib>Damasceno, Marta Maria Coelho</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of nursing practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Araújo, Márcio Flávio Moura</au><au>dos Santos Alves, Priscila de Jesus</au><au>Veras, Vivian Saraiva</au><au>de Araújo, Thiago Moura</au><au>Zanetti, Maria Lúcia</au><au>Damasceno, Marta Maria Coelho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Drug interactions in Brazilian type 2 diabetes patients</atitle><jtitle>International journal of nursing practice</jtitle><addtitle>Int J Nurs Pract</addtitle><date>2013-08</date><risdate>2013</risdate><volume>19</volume><issue>4</issue><spage>423</spage><epage>430</epage><pages>423-430</pages><issn>1322-7114</issn><eissn>1440-172X</eissn><abstract>The aim of this paper is to identify the prevalence of the most frequent drug interactions in patients using oral antidiabéticos and their association with capillary glucose and medication adherence. 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| subjects | Adherence Adolescent Adult Aged Aged, 80 and over antihypertensives Brazil Comorbidity Cross-Sectional Studies Diabetes Diabetes Mellitus, Type 2 - drug therapy Diabetics Drug Interactions Drugs Female Glucose Humans hypoglycaemics Hypoglycemic Agents - pharmacology Hypoglycemic Agents - therapeutic use Male Middle Aged Nursing Patient Compliance Patients Pharmacology Prevalence Type 2 diabetes mellitus |
| title | Drug interactions in Brazilian type 2 diabetes patients |
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