Effects and Interactions of Natural Cannabinoids on the Isolated Heart

Abstract A Langendorff perfused rat heart preparation was designed to process dose-response effects of cardioactive drugs on rate, coronary flow, and supraaortic differential pressure (ΔP; an index of cardiac performance). In this preparation, Δ9--tetrahydrocannabinol (THC) 2 × 10-6 M to 10-5 M indu...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1985-11, Vol.180 (2), p.312-316
Hauptverfasser:	Nahas, Gabriel, Trouve, Renaud
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Pressure - drug effects Cannabidiol - pharmacology Cannabidiol - toxicity Cannabinoids - pharmacology Cannabinoids - toxicity Cannabinol - pharmacology Cannabinol - toxicity Cardiac Output - drug effects Coronary Circulation - drug effects Dose-Response Relationship, Drug Drug addictions Heart - drug effects Heart - physiopathology Heart Rate - drug effects Hemodynamics - drug effects Medical sciences Rats Rats, Inbred Strains Tachycardia - chemically induced Toxicology
Online-Zugang:	Volltext
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