Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway. e69619

NOD2 is an intracellular pattern recognition receptor that assembles with receptor-interacting protein (RIP)-2 kinase in response to the presence of bacterial muramyl dipeptide (MDP) in the host cell cytoplasm, thereby inducing signals leading to the production of pro-inflammatory cytokines. The dys...

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Veröffentlicht in:	PloS one 2013-08, Vol.8 (8)
Hauptverfasser:	Rickard, David J, Sehon, Clark A, Kasparcova, Viera, Kallal, Lorena A, Zeng, Xin, Montoute, Monica N, Chordia, Tushar, Poore, Derek D, Li, Hu, Wu, Zining
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzimidazole
Online-Zugang:	Volltext
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