S-Nitrosoglutathione Reductase Inhibition Regulates Allergen-Induced Lung Inflammation and Airway Hyperreactivity. e70351

Allergic asthma is characterized by Th2 type inflammation, leading to airway hyperresponsivenes, mucus hypersecretion and tissue remodeling. S-Nitrosoglutathione reductase (GSNOR) is an alcohol dehydrogenase involved in the regulation of intracellular levels of S-nitrosothiols. GSNOR activity has be...

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Veröffentlicht in:PloS one 2013-07, Vol.8 (7)
Hauptverfasser: Ferrini, Maria E, Simons, Bryan J, Bassett, David JP, Bradley, Matthews O, Roberts, Kevan, Jaffar, Zeina
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Sprache:eng
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