Evaluation of parasitological and immunological aspects of acute infection by Ancylostoma caninum and Ancylostoma braziliense in mixed-breed dogs
This study compared the course of infection by Ancylostoma caninum and Ancylostoma braziliense in mixed-breed dogs infected with L 3 larvae. Dogs infected with A. caninum eliminated more eggs than did those infected with A. braziliense . A total of 38 % of A. caninum and 44 % of A. braziliense larva...
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| Veröffentlicht in: | Parasitology research (1987) 2013-06, Vol.112 (6), p.2151-2157 |
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| container_title | Parasitology research (1987) |
| container_volume | 112 |
| creator | Dias, Sílvia Regina Costa Cunha, Denílson Eduardo Silva da Silva, Sydnei Magno dos Santos, Hudson Andrade Fujiwara, Ricardo Toshio Rabelo, Élida Mara Leite |
| description | This study compared the course of infection by
Ancylostoma caninum
and
Ancylostoma braziliense
in mixed-breed dogs infected with L
3
larvae. Dogs infected with
A. caninum
eliminated more eggs than did those infected with
A. braziliense
. A total of 38 % of
A. caninum
and 44 % of
A. braziliense
larvae were recovered as adult worms. There were no marked clinical abnormalities in dogs with either infection.
A. caninum
was associated with anemia and an increased number of circulating neutrophils, whereas infection with
A. braziliense
led to a decrease in the number of leukocytes. The humoral response against excreted and secreted antigens from adult worms was more sensitive and specific than the response induced with the crude antigen. No immune response was observed for either crude or excreted-secreted (ES) antigens from larvae of either species. A nonspecific response against the crude antigen of
A. braziliense
was found at 0 and 7 days postinfection and maintained throughout the infection period. However, antibody titers against ES antigens were elevated in
A. caninum
infection at patency and death, showing that this antigen has a higher specificity. The immune response elicited by infection with
A. braziliense
in dogs has not been described previously. No significant differences were observed in the infection processes of the two
Ancylostoma
species, except for the higher number of eggs eliminated from dogs infected with
A. caninum
, which may indicate a better evolutionary adaptation of the parasite to its host in comparison with
A. braziliense
. |
| doi_str_mv | 10.1007/s00436-013-3370-y |
| format | Article |
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Ancylostoma caninum
and
Ancylostoma braziliense
in mixed-breed dogs infected with L
3
larvae. Dogs infected with
A. caninum
eliminated more eggs than did those infected with
A. braziliense
. A total of 38 % of
A. caninum
and 44 % of
A. braziliense
larvae were recovered as adult worms. There were no marked clinical abnormalities in dogs with either infection.
A. caninum
was associated with anemia and an increased number of circulating neutrophils, whereas infection with
A. braziliense
led to a decrease in the number of leukocytes. The humoral response against excreted and secreted antigens from adult worms was more sensitive and specific than the response induced with the crude antigen. No immune response was observed for either crude or excreted-secreted (ES) antigens from larvae of either species. A nonspecific response against the crude antigen of
A. braziliense
was found at 0 and 7 days postinfection and maintained throughout the infection period. However, antibody titers against ES antigens were elevated in
A. caninum
infection at patency and death, showing that this antigen has a higher specificity. The immune response elicited by infection with
A. braziliense
in dogs has not been described previously. No significant differences were observed in the infection processes of the two
Ancylostoma
species, except for the higher number of eggs eliminated from dogs infected with
A. caninum
, which may indicate a better evolutionary adaptation of the parasite to its host in comparison with
A. braziliense
.</description><identifier>ISSN: 0932-0113</identifier><identifier>EISSN: 1432-1955</identifier><identifier>DOI: 10.1007/s00436-013-3370-y</identifier><identifier>PMID: 23494155</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Ancylostoma - pathogenicity ; Ancylostoma caninum ; Ancylostomiasis - complications ; Ancylostomiasis - immunology ; Ancylostomiasis - parasitology ; Ancylostomiasis - pathology ; Anemia - etiology ; Animals ; Antibodies, Helminth - blood ; Biomedical and Life Sciences ; Biomedicine ; Disease Models, Animal ; Dog Diseases - parasitology ; Dog Diseases - pathology ; Dogs ; Feces - parasitology ; Health aspects ; Host-parasite relationships ; Immunology ; Leukocytosis - etiology ; Medical Microbiology ; Microbiology ; Nematoda ; Neutropenia - etiology ; Original Paper ; Parasite Egg Count ; Physiological aspects</subject><ispartof>Parasitology research (1987), 2013-06, Vol.112 (6), p.2151-2157</ispartof><rights>Springer-Verlag Berlin Heidelberg 2013</rights><rights>COPYRIGHT 2013 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-18c73728b6438618073de21450ea46c0fa9232f8361f3270fb6af7977bc16a2a3</citedby><cites>FETCH-LOGICAL-c444t-18c73728b6438618073de21450ea46c0fa9232f8361f3270fb6af7977bc16a2a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00436-013-3370-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00436-013-3370-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23494155$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dias, Sílvia Regina Costa</creatorcontrib><creatorcontrib>Cunha, Denílson Eduardo Silva</creatorcontrib><creatorcontrib>da Silva, Sydnei Magno</creatorcontrib><creatorcontrib>dos Santos, Hudson Andrade</creatorcontrib><creatorcontrib>Fujiwara, Ricardo Toshio</creatorcontrib><creatorcontrib>Rabelo, Élida Mara Leite</creatorcontrib><title>Evaluation of parasitological and immunological aspects of acute infection by Ancylostoma caninum and Ancylostoma braziliense in mixed-breed dogs</title><title>Parasitology research (1987)</title><addtitle>Parasitol Res</addtitle><addtitle>Parasitol Res</addtitle><description>This study compared the course of infection by
Ancylostoma caninum
and
Ancylostoma braziliense
in mixed-breed dogs infected with L
3
larvae. Dogs infected with
A. caninum
eliminated more eggs than did those infected with
A. braziliense
. A total of 38 % of
A. caninum
and 44 % of
A. braziliense
larvae were recovered as adult worms. There were no marked clinical abnormalities in dogs with either infection.
A. caninum
was associated with anemia and an increased number of circulating neutrophils, whereas infection with
A. braziliense
led to a decrease in the number of leukocytes. The humoral response against excreted and secreted antigens from adult worms was more sensitive and specific than the response induced with the crude antigen. No immune response was observed for either crude or excreted-secreted (ES) antigens from larvae of either species. A nonspecific response against the crude antigen of
A. braziliense
was found at 0 and 7 days postinfection and maintained throughout the infection period. However, antibody titers against ES antigens were elevated in
A. caninum
infection at patency and death, showing that this antigen has a higher specificity. The immune response elicited by infection with
A. braziliense
in dogs has not been described previously. No significant differences were observed in the infection processes of the two
Ancylostoma
species, except for the higher number of eggs eliminated from dogs infected with
A. caninum
, which may indicate a better evolutionary adaptation of the parasite to its host in comparison with
A. braziliense
.</description><subject>Ancylostoma - pathogenicity</subject><subject>Ancylostoma caninum</subject><subject>Ancylostomiasis - complications</subject><subject>Ancylostomiasis - immunology</subject><subject>Ancylostomiasis - parasitology</subject><subject>Ancylostomiasis - pathology</subject><subject>Anemia - etiology</subject><subject>Animals</subject><subject>Antibodies, Helminth - blood</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Disease Models, Animal</subject><subject>Dog Diseases - parasitology</subject><subject>Dog Diseases - pathology</subject><subject>Dogs</subject><subject>Feces - parasitology</subject><subject>Health aspects</subject><subject>Host-parasite relationships</subject><subject>Immunology</subject><subject>Leukocytosis - etiology</subject><subject>Medical Microbiology</subject><subject>Microbiology</subject><subject>Nematoda</subject><subject>Neutropenia - etiology</subject><subject>Original Paper</subject><subject>Parasite Egg Count</subject><subject>Physiological aspects</subject><issn>0932-0113</issn><issn>1432-1955</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk2L1TAUhoMoznX0B7iRgpvZdDz5aNIuL8M4CgNudB1O0-SSoU2uSSte_4X_2NSOXyBKFglvnvdwOOcl5DmFSwqgXmUAwWUNlNecK6hPD8iOCs5q2jXNQ7KDrryBUn5GnuR8B0CVFOIxOWNcdII2zY58vf6E44Kzj6GKrjpiwuznOMaDNzhWGIbKT9MSfin5aM2cVxjNMtvKB1eE1d-fqn0wpzHmOU5YGQw-LNP3Gr_rfcIvfvQ25NVcTf6zHeo-WTtUQzzkp-SRwzHbZ_f3Ofnw-vr91Zv69t3N26v9bW2EEHNNW6O4Ym0vBW8lbUHxwTIqGrAopAGHHePMtVxSx5kC10t0qlOqN1QiQ35OLra6xxQ_LjbPevLZ2HHEYOOSdRkktE3XMvl_lDeSdxw6KOjLDT3gaHWZTZwTmhXXey4oZaVRUajLv1DlDHbyJgbrfNH_MNDNYFLMOVmnj8lPmE6agl6zoLcs6JIFvWZBn4rnxX3XSz_Z4afjx_ILwDYgl69wsEnfxSWFMvR_VP0GO4m_tg</recordid><startdate>20130601</startdate><enddate>20130601</enddate><creator>Dias, Sílvia Regina Costa</creator><creator>Cunha, Denílson Eduardo Silva</creator><creator>da Silva, Sydnei Magno</creator><creator>dos Santos, Hudson Andrade</creator><creator>Fujiwara, Ricardo Toshio</creator><creator>Rabelo, Élida Mara Leite</creator><general>Springer-Verlag</general><general>Springer</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope><scope>M7N</scope></search><sort><creationdate>20130601</creationdate><title>Evaluation of parasitological and immunological aspects of acute infection by Ancylostoma caninum and Ancylostoma braziliense in mixed-breed dogs</title><author>Dias, Sílvia Regina Costa ; Cunha, Denílson Eduardo Silva ; da Silva, Sydnei Magno ; dos Santos, Hudson Andrade ; Fujiwara, Ricardo Toshio ; Rabelo, Élida Mara Leite</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-18c73728b6438618073de21450ea46c0fa9232f8361f3270fb6af7977bc16a2a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Ancylostoma - pathogenicity</topic><topic>Ancylostoma caninum</topic><topic>Ancylostomiasis - complications</topic><topic>Ancylostomiasis - immunology</topic><topic>Ancylostomiasis - parasitology</topic><topic>Ancylostomiasis - pathology</topic><topic>Anemia - etiology</topic><topic>Animals</topic><topic>Antibodies, Helminth - blood</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Disease Models, Animal</topic><topic>Dog Diseases - parasitology</topic><topic>Dog Diseases - pathology</topic><topic>Dogs</topic><topic>Feces - parasitology</topic><topic>Health aspects</topic><topic>Host-parasite relationships</topic><topic>Immunology</topic><topic>Leukocytosis - etiology</topic><topic>Medical Microbiology</topic><topic>Microbiology</topic><topic>Nematoda</topic><topic>Neutropenia - etiology</topic><topic>Original Paper</topic><topic>Parasite Egg Count</topic><topic>Physiological aspects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dias, Sílvia Regina Costa</creatorcontrib><creatorcontrib>Cunha, Denílson Eduardo Silva</creatorcontrib><creatorcontrib>da Silva, Sydnei Magno</creatorcontrib><creatorcontrib>dos Santos, Hudson Andrade</creatorcontrib><creatorcontrib>Fujiwara, Ricardo Toshio</creatorcontrib><creatorcontrib>Rabelo, Élida Mara Leite</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><jtitle>Parasitology research (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dias, Sílvia Regina Costa</au><au>Cunha, Denílson Eduardo Silva</au><au>da Silva, Sydnei Magno</au><au>dos Santos, Hudson Andrade</au><au>Fujiwara, Ricardo Toshio</au><au>Rabelo, Élida Mara Leite</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of parasitological and immunological aspects of acute infection by Ancylostoma caninum and Ancylostoma braziliense in mixed-breed dogs</atitle><jtitle>Parasitology research (1987)</jtitle><stitle>Parasitol Res</stitle><addtitle>Parasitol Res</addtitle><date>2013-06-01</date><risdate>2013</risdate><volume>112</volume><issue>6</issue><spage>2151</spage><epage>2157</epage><pages>2151-2157</pages><issn>0932-0113</issn><eissn>1432-1955</eissn><abstract>This study compared the course of infection by
Ancylostoma caninum
and
Ancylostoma braziliense
in mixed-breed dogs infected with L
3
larvae. Dogs infected with
A. caninum
eliminated more eggs than did those infected with
A. braziliense
. A total of 38 % of
A. caninum
and 44 % of
A. braziliense
larvae were recovered as adult worms. There were no marked clinical abnormalities in dogs with either infection.
A. caninum
was associated with anemia and an increased number of circulating neutrophils, whereas infection with
A. braziliense
led to a decrease in the number of leukocytes. The humoral response against excreted and secreted antigens from adult worms was more sensitive and specific than the response induced with the crude antigen. No immune response was observed for either crude or excreted-secreted (ES) antigens from larvae of either species. A nonspecific response against the crude antigen of
A. braziliense
was found at 0 and 7 days postinfection and maintained throughout the infection period. However, antibody titers against ES antigens were elevated in
A. caninum
infection at patency and death, showing that this antigen has a higher specificity. The immune response elicited by infection with
A. braziliense
in dogs has not been described previously. No significant differences were observed in the infection processes of the two
Ancylostoma
species, except for the higher number of eggs eliminated from dogs infected with
A. caninum
, which may indicate a better evolutionary adaptation of the parasite to its host in comparison with
A. braziliense
.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>23494155</pmid><doi>10.1007/s00436-013-3370-y</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0932-0113 |
| ispartof | Parasitology research (1987), 2013-06, Vol.112 (6), p.2151-2157 |
| issn | 0932-0113 1432-1955 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1430859826 |
| source | MEDLINE; Springer Online Journals Complete |
| subjects | Ancylostoma - pathogenicity Ancylostoma caninum Ancylostomiasis - complications Ancylostomiasis - immunology Ancylostomiasis - parasitology Ancylostomiasis - pathology Anemia - etiology Animals Antibodies, Helminth - blood Biomedical and Life Sciences Biomedicine Disease Models, Animal Dog Diseases - parasitology Dog Diseases - pathology Dogs Feces - parasitology Health aspects Host-parasite relationships Immunology Leukocytosis - etiology Medical Microbiology Microbiology Nematoda Neutropenia - etiology Original Paper Parasite Egg Count Physiological aspects |
| title | Evaluation of parasitological and immunological aspects of acute infection by Ancylostoma caninum and Ancylostoma braziliense in mixed-breed dogs |
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