Eco-friendly approach using marine actinobacteria and its compounds to control ticks and mosquitoes
Ticks and mosquitoes are ectoparasitic arthropods that can transmit a variety of diseases to humans and animals during blood feeding and causing serious infectious disorders. The purpose of the present study was to assess the acaricidal and insecticidal property of ethyl acetate extract and its comp...
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| Veröffentlicht in: | Parasitology research (1987) 2013-02, Vol.112 (2), p.719-729 |
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| creator | Thenmozhi, Mohankumar Gopal, Jannu Vinay Kannabiran, Krishnan Rajakumar, Govindasamy Velayutham, Kanayairam Rahuman, Abdul Abdul |
| description | Ticks and mosquitoes are ectoparasitic arthropods that can transmit a variety of diseases to humans and animals during blood feeding and causing serious infectious disorders. The purpose of the present study was to assess the acaricidal and insecticidal property of ethyl acetate extract and its compounds isolated from marine actinobacteria,
Streptomyces
VITSTK7 sp. against the larvae of cattle ticks,
Haemaphysalis bispinosa
and
Rhipicephalus
(
Boophilus
)
microplus
(Acari: Ixodidae); fourth-instar larvae of malaria vector,
Anopheles subpictus
; and filarial vector,
Culex quinquefasciatus
(Diptera: Culicidae). The ethyl acetate extract was loaded on silica gel column and separated with chloroform, methanol, and acetone as the solvents system. The separation of fractions was visualized by the thin layer chromatography (TLC) plate, further confirmed by high-performance liquid chromatography, and followed by gas liquid chromatography. Three major fractions were analyzed in mass spectroscopy (MS) and matched with existing compounds in the data base. Based on the fragment pattern, it led to the major compounds which were predicted as cyclopentanepropanoic acid, 3,5-bis(acetyloxy)-2-[3-(methoxyimino)octyl], methyl ester (13.3 %)
1
; 5-azidomethyl-3-(2-ethoxy carbonyl-ethyl)-4-ethoxycarbonylmethyl-1
H
-pyrrole-2-carboxylic acid, ethyl ester (18.2 %)
2
; and akuammilan-16-carboxylic acid, 17-(acetyloxy)-10-methoxy, methyl ester (16R) (53.3 %)
3
. The maximum efficacy was observed in compounds
1
,
2
, and
3
, and the ethyl acetate extract of
Streptomyces
VITSTK7 sp. against the larvae of
H
.
bispinosa
(LC
50
= 1,573.36, 1,333.09, 1,073.29, and 409.71 ppm;
r
2
= 0.0.990, 0.934, 0.935, and 0.908),
R. microplus
(LC
50
= 1,877.86, 815.83, 1,631.14, and 441.54 ppm;
r
2
= 0.981, 0.926, 0.0970, and 0.915),
A. subpictus
(LC
50
= 273.89, 687.69, 464.75, and 223.83 ppm;
r
2
= 0.758, 0.924, 0.841, and 0.902), and
C
.
quinquefasciatus
(LC
50
= 430.06, 881.59, 777.0, and 195.70 ppm;
r
2
= 0.839, 0.859, 0.870, and 0.882), respectively. Results of the present study provide evidence that the maximum parasitic activity of ethyl acetate extract and a synergistic effect of combinations of different compounds have been suggested. The control (distilled water) showed nil mortality in the concurrent assay. In the present study, a novel, targeted, simple, and eco-friendly approach has been suggested to control blood-feeding parasites. |
| doi_str_mv | 10.1007/s00436-012-3192-3 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1430859745</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A336603675</galeid><sourcerecordid>A336603675</sourcerecordid><originalsourceid>FETCH-LOGICAL-c416t-f3fcb2b402c65055b8e8cf69effc86764b599fe0b7566b298908d20627880b9e3</originalsourceid><addsrcrecordid>eNp9UUFvFiEQJUZjP6s_wIvh6GXrAAsLx6Zp1aSJFz0TYOGTugtfgT3038vnVo-GZAaG9yYz7yH0nsAVAZg-VYCRiQEIHRhRPbxABzIyOhDF-Ut0ANXvQAi7QG9qfQAgkxjH1-iCMiI7azogd-vyEEr0aV6esDmdSjbuJ95qTEe8mhKTx8a1mLLtyZdosEkzjq1il9dT3tJcccv9kVrJC27R_ap_IGuuj1ts2de36FUwS_XvnvMl-nF3-_3my3D_7fPXm-v7wY1EtCGw4Cy1I1AnOHBupZcuCOVDcFL0yS1XKniwExfCUiUVyJmCoJOUYJVnl-jj3rcv8bj52vQaq_PLYpLPW9VdGpBcTSPv0KsdejSL1zGF3Ipx_cx-jX0XH2KvXzMmBDAxnQlkJ7iSay0-6FOJXZ8nTUCfzdC7GbrLqs9maNY5H57n2ezq53-Mv-p3AN0BtX-loy_6IW8ldY3-0_U3jHKVEQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1430859745</pqid></control><display><type>article</type><title>Eco-friendly approach using marine actinobacteria and its compounds to control ticks and mosquitoes</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Thenmozhi, Mohankumar ; Gopal, Jannu Vinay ; Kannabiran, Krishnan ; Rajakumar, Govindasamy ; Velayutham, Kanayairam ; Rahuman, Abdul Abdul</creator><creatorcontrib>Thenmozhi, Mohankumar ; Gopal, Jannu Vinay ; Kannabiran, Krishnan ; Rajakumar, Govindasamy ; Velayutham, Kanayairam ; Rahuman, Abdul Abdul</creatorcontrib><description>Ticks and mosquitoes are ectoparasitic arthropods that can transmit a variety of diseases to humans and animals during blood feeding and causing serious infectious disorders. The purpose of the present study was to assess the acaricidal and insecticidal property of ethyl acetate extract and its compounds isolated from marine actinobacteria,
Streptomyces
VITSTK7 sp. against the larvae of cattle ticks,
Haemaphysalis bispinosa
and
Rhipicephalus
(
Boophilus
)
microplus
(Acari: Ixodidae); fourth-instar larvae of malaria vector,
Anopheles subpictus
; and filarial vector,
Culex quinquefasciatus
(Diptera: Culicidae). The ethyl acetate extract was loaded on silica gel column and separated with chloroform, methanol, and acetone as the solvents system. The separation of fractions was visualized by the thin layer chromatography (TLC) plate, further confirmed by high-performance liquid chromatography, and followed by gas liquid chromatography. Three major fractions were analyzed in mass spectroscopy (MS) and matched with existing compounds in the data base. Based on the fragment pattern, it led to the major compounds which were predicted as cyclopentanepropanoic acid, 3,5-bis(acetyloxy)-2-[3-(methoxyimino)octyl], methyl ester (13.3 %)
1
; 5-azidomethyl-3-(2-ethoxy carbonyl-ethyl)-4-ethoxycarbonylmethyl-1
H
-pyrrole-2-carboxylic acid, ethyl ester (18.2 %)
2
; and akuammilan-16-carboxylic acid, 17-(acetyloxy)-10-methoxy, methyl ester (16R) (53.3 %)
3
. The maximum efficacy was observed in compounds
1
,
2
, and
3
, and the ethyl acetate extract of
Streptomyces
VITSTK7 sp. against the larvae of
H
.
bispinosa
(LC
50
= 1,573.36, 1,333.09, 1,073.29, and 409.71 ppm;
r
2
= 0.0.990, 0.934, 0.935, and 0.908),
R. microplus
(LC
50
= 1,877.86, 815.83, 1,631.14, and 441.54 ppm;
r
2
= 0.981, 0.926, 0.0970, and 0.915),
A. subpictus
(LC
50
= 273.89, 687.69, 464.75, and 223.83 ppm;
r
2
= 0.758, 0.924, 0.841, and 0.902), and
C
.
quinquefasciatus
(LC
50
= 430.06, 881.59, 777.0, and 195.70 ppm;
r
2
= 0.839, 0.859, 0.870, and 0.882), respectively. Results of the present study provide evidence that the maximum parasitic activity of ethyl acetate extract and a synergistic effect of combinations of different compounds have been suggested. The control (distilled water) showed nil mortality in the concurrent assay. In the present study, a novel, targeted, simple, and eco-friendly approach has been suggested to control blood-feeding parasites.</description><identifier>ISSN: 0932-0113</identifier><identifier>EISSN: 1432-1955</identifier><identifier>DOI: 10.1007/s00436-012-3192-3</identifier><identifier>PMID: 23180127</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Acari ; Acaricides - chemistry ; Acaricides - isolation & purification ; Acaricides - pharmacology ; Actinobacteria ; Actinomycetes ; Animals ; Anopheles - drug effects ; Anopheles subpictus ; Arthropoda ; Biological Assay ; Biological control ; Biological Products - chemistry ; Biological Products - isolation & purification ; Biological Products - pharmacology ; Biomedical and Life Sciences ; Biomedicine ; Boophilus microplus ; Chromatography ; Control ; Culex - drug effects ; Culex quinquefasciatus ; Culicidae ; Diptera ; Environmental aspects ; Haemaphysalis ; Health aspects ; Immunology ; Insecticides - chemistry ; Insecticides - isolation & purification ; Insecticides - pharmacology ; Ixodidae ; Ixodidae - drug effects ; Larva - drug effects ; Mass Spectrometry ; Medical Microbiology ; Microbiology ; Mosquitoes ; Original Paper ; Pests ; Rhipicephalus ; Streptomyces ; Streptomyces - chemistry ; Streptomyces - isolation & purification ; Survival Analysis ; Ticks ; Water Microbiology</subject><ispartof>Parasitology research (1987), 2013-02, Vol.112 (2), p.719-729</ispartof><rights>Springer-Verlag Berlin Heidelberg 2012</rights><rights>COPYRIGHT 2013 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c416t-f3fcb2b402c65055b8e8cf69effc86764b599fe0b7566b298908d20627880b9e3</citedby><cites>FETCH-LOGICAL-c416t-f3fcb2b402c65055b8e8cf69effc86764b599fe0b7566b298908d20627880b9e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00436-012-3192-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00436-012-3192-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23180127$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thenmozhi, Mohankumar</creatorcontrib><creatorcontrib>Gopal, Jannu Vinay</creatorcontrib><creatorcontrib>Kannabiran, Krishnan</creatorcontrib><creatorcontrib>Rajakumar, Govindasamy</creatorcontrib><creatorcontrib>Velayutham, Kanayairam</creatorcontrib><creatorcontrib>Rahuman, Abdul Abdul</creatorcontrib><title>Eco-friendly approach using marine actinobacteria and its compounds to control ticks and mosquitoes</title><title>Parasitology research (1987)</title><addtitle>Parasitol Res</addtitle><addtitle>Parasitol Res</addtitle><description>Ticks and mosquitoes are ectoparasitic arthropods that can transmit a variety of diseases to humans and animals during blood feeding and causing serious infectious disorders. The purpose of the present study was to assess the acaricidal and insecticidal property of ethyl acetate extract and its compounds isolated from marine actinobacteria,
Streptomyces
VITSTK7 sp. against the larvae of cattle ticks,
Haemaphysalis bispinosa
and
Rhipicephalus
(
Boophilus
)
microplus
(Acari: Ixodidae); fourth-instar larvae of malaria vector,
Anopheles subpictus
; and filarial vector,
Culex quinquefasciatus
(Diptera: Culicidae). The ethyl acetate extract was loaded on silica gel column and separated with chloroform, methanol, and acetone as the solvents system. The separation of fractions was visualized by the thin layer chromatography (TLC) plate, further confirmed by high-performance liquid chromatography, and followed by gas liquid chromatography. Three major fractions were analyzed in mass spectroscopy (MS) and matched with existing compounds in the data base. Based on the fragment pattern, it led to the major compounds which were predicted as cyclopentanepropanoic acid, 3,5-bis(acetyloxy)-2-[3-(methoxyimino)octyl], methyl ester (13.3 %)
1
; 5-azidomethyl-3-(2-ethoxy carbonyl-ethyl)-4-ethoxycarbonylmethyl-1
H
-pyrrole-2-carboxylic acid, ethyl ester (18.2 %)
2
; and akuammilan-16-carboxylic acid, 17-(acetyloxy)-10-methoxy, methyl ester (16R) (53.3 %)
3
. The maximum efficacy was observed in compounds
1
,
2
, and
3
, and the ethyl acetate extract of
Streptomyces
VITSTK7 sp. against the larvae of
H
.
bispinosa
(LC
50
= 1,573.36, 1,333.09, 1,073.29, and 409.71 ppm;
r
2
= 0.0.990, 0.934, 0.935, and 0.908),
R. microplus
(LC
50
= 1,877.86, 815.83, 1,631.14, and 441.54 ppm;
r
2
= 0.981, 0.926, 0.0970, and 0.915),
A. subpictus
(LC
50
= 273.89, 687.69, 464.75, and 223.83 ppm;
r
2
= 0.758, 0.924, 0.841, and 0.902), and
C
.
quinquefasciatus
(LC
50
= 430.06, 881.59, 777.0, and 195.70 ppm;
r
2
= 0.839, 0.859, 0.870, and 0.882), respectively. Results of the present study provide evidence that the maximum parasitic activity of ethyl acetate extract and a synergistic effect of combinations of different compounds have been suggested. The control (distilled water) showed nil mortality in the concurrent assay. In the present study, a novel, targeted, simple, and eco-friendly approach has been suggested to control blood-feeding parasites.</description><subject>Acari</subject><subject>Acaricides - chemistry</subject><subject>Acaricides - isolation & purification</subject><subject>Acaricides - pharmacology</subject><subject>Actinobacteria</subject><subject>Actinomycetes</subject><subject>Animals</subject><subject>Anopheles - drug effects</subject><subject>Anopheles subpictus</subject><subject>Arthropoda</subject><subject>Biological Assay</subject><subject>Biological control</subject><subject>Biological Products - chemistry</subject><subject>Biological Products - isolation & purification</subject><subject>Biological Products - pharmacology</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Boophilus microplus</subject><subject>Chromatography</subject><subject>Control</subject><subject>Culex - drug effects</subject><subject>Culex quinquefasciatus</subject><subject>Culicidae</subject><subject>Diptera</subject><subject>Environmental aspects</subject><subject>Haemaphysalis</subject><subject>Health aspects</subject><subject>Immunology</subject><subject>Insecticides - chemistry</subject><subject>Insecticides - isolation & purification</subject><subject>Insecticides - pharmacology</subject><subject>Ixodidae</subject><subject>Ixodidae - drug effects</subject><subject>Larva - drug effects</subject><subject>Mass Spectrometry</subject><subject>Medical Microbiology</subject><subject>Microbiology</subject><subject>Mosquitoes</subject><subject>Original Paper</subject><subject>Pests</subject><subject>Rhipicephalus</subject><subject>Streptomyces</subject><subject>Streptomyces - chemistry</subject><subject>Streptomyces - isolation & purification</subject><subject>Survival Analysis</subject><subject>Ticks</subject><subject>Water Microbiology</subject><issn>0932-0113</issn><issn>1432-1955</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UUFvFiEQJUZjP6s_wIvh6GXrAAsLx6Zp1aSJFz0TYOGTugtfgT3038vnVo-GZAaG9yYz7yH0nsAVAZg-VYCRiQEIHRhRPbxABzIyOhDF-Ut0ANXvQAi7QG9qfQAgkxjH1-iCMiI7azogd-vyEEr0aV6esDmdSjbuJ95qTEe8mhKTx8a1mLLtyZdosEkzjq1il9dT3tJcccv9kVrJC27R_ap_IGuuj1ts2de36FUwS_XvnvMl-nF3-_3my3D_7fPXm-v7wY1EtCGw4Cy1I1AnOHBupZcuCOVDcFL0yS1XKniwExfCUiUVyJmCoJOUYJVnl-jj3rcv8bj52vQaq_PLYpLPW9VdGpBcTSPv0KsdejSL1zGF3Ipx_cx-jX0XH2KvXzMmBDAxnQlkJ7iSay0-6FOJXZ8nTUCfzdC7GbrLqs9maNY5H57n2ezq53-Mv-p3AN0BtX-loy_6IW8ldY3-0_U3jHKVEQ</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Thenmozhi, Mohankumar</creator><creator>Gopal, Jannu Vinay</creator><creator>Kannabiran, Krishnan</creator><creator>Rajakumar, Govindasamy</creator><creator>Velayutham, Kanayairam</creator><creator>Rahuman, Abdul Abdul</creator><general>Springer-Verlag</general><general>Springer</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7TN</scope><scope>C1K</scope><scope>F1W</scope><scope>H95</scope><scope>H97</scope><scope>L.G</scope><scope>M7N</scope></search><sort><creationdate>20130201</creationdate><title>Eco-friendly approach using marine actinobacteria and its compounds to control ticks and mosquitoes</title><author>Thenmozhi, Mohankumar ; Gopal, Jannu Vinay ; Kannabiran, Krishnan ; Rajakumar, Govindasamy ; Velayutham, Kanayairam ; Rahuman, Abdul Abdul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-f3fcb2b402c65055b8e8cf69effc86764b599fe0b7566b298908d20627880b9e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acari</topic><topic>Acaricides - chemistry</topic><topic>Acaricides - isolation & purification</topic><topic>Acaricides - pharmacology</topic><topic>Actinobacteria</topic><topic>Actinomycetes</topic><topic>Animals</topic><topic>Anopheles - drug effects</topic><topic>Anopheles subpictus</topic><topic>Arthropoda</topic><topic>Biological Assay</topic><topic>Biological control</topic><topic>Biological Products - chemistry</topic><topic>Biological Products - isolation & purification</topic><topic>Biological Products - pharmacology</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Boophilus microplus</topic><topic>Chromatography</topic><topic>Control</topic><topic>Culex - drug effects</topic><topic>Culex quinquefasciatus</topic><topic>Culicidae</topic><topic>Diptera</topic><topic>Environmental aspects</topic><topic>Haemaphysalis</topic><topic>Health aspects</topic><topic>Immunology</topic><topic>Insecticides - chemistry</topic><topic>Insecticides - isolation & purification</topic><topic>Insecticides - pharmacology</topic><topic>Ixodidae</topic><topic>Ixodidae - drug effects</topic><topic>Larva - drug effects</topic><topic>Mass Spectrometry</topic><topic>Medical Microbiology</topic><topic>Microbiology</topic><topic>Mosquitoes</topic><topic>Original Paper</topic><topic>Pests</topic><topic>Rhipicephalus</topic><topic>Streptomyces</topic><topic>Streptomyces - chemistry</topic><topic>Streptomyces - isolation & purification</topic><topic>Survival Analysis</topic><topic>Ticks</topic><topic>Water Microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thenmozhi, Mohankumar</creatorcontrib><creatorcontrib>Gopal, Jannu Vinay</creatorcontrib><creatorcontrib>Kannabiran, Krishnan</creatorcontrib><creatorcontrib>Rajakumar, Govindasamy</creatorcontrib><creatorcontrib>Velayutham, Kanayairam</creatorcontrib><creatorcontrib>Rahuman, Abdul Abdul</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Oceanic Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><jtitle>Parasitology research (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thenmozhi, Mohankumar</au><au>Gopal, Jannu Vinay</au><au>Kannabiran, Krishnan</au><au>Rajakumar, Govindasamy</au><au>Velayutham, Kanayairam</au><au>Rahuman, Abdul Abdul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Eco-friendly approach using marine actinobacteria and its compounds to control ticks and mosquitoes</atitle><jtitle>Parasitology research (1987)</jtitle><stitle>Parasitol Res</stitle><addtitle>Parasitol Res</addtitle><date>2013-02-01</date><risdate>2013</risdate><volume>112</volume><issue>2</issue><spage>719</spage><epage>729</epage><pages>719-729</pages><issn>0932-0113</issn><eissn>1432-1955</eissn><abstract>Ticks and mosquitoes are ectoparasitic arthropods that can transmit a variety of diseases to humans and animals during blood feeding and causing serious infectious disorders. The purpose of the present study was to assess the acaricidal and insecticidal property of ethyl acetate extract and its compounds isolated from marine actinobacteria,
Streptomyces
VITSTK7 sp. against the larvae of cattle ticks,
Haemaphysalis bispinosa
and
Rhipicephalus
(
Boophilus
)
microplus
(Acari: Ixodidae); fourth-instar larvae of malaria vector,
Anopheles subpictus
; and filarial vector,
Culex quinquefasciatus
(Diptera: Culicidae). The ethyl acetate extract was loaded on silica gel column and separated with chloroform, methanol, and acetone as the solvents system. The separation of fractions was visualized by the thin layer chromatography (TLC) plate, further confirmed by high-performance liquid chromatography, and followed by gas liquid chromatography. Three major fractions were analyzed in mass spectroscopy (MS) and matched with existing compounds in the data base. Based on the fragment pattern, it led to the major compounds which were predicted as cyclopentanepropanoic acid, 3,5-bis(acetyloxy)-2-[3-(methoxyimino)octyl], methyl ester (13.3 %)
1
; 5-azidomethyl-3-(2-ethoxy carbonyl-ethyl)-4-ethoxycarbonylmethyl-1
H
-pyrrole-2-carboxylic acid, ethyl ester (18.2 %)
2
; and akuammilan-16-carboxylic acid, 17-(acetyloxy)-10-methoxy, methyl ester (16R) (53.3 %)
3
. The maximum efficacy was observed in compounds
1
,
2
, and
3
, and the ethyl acetate extract of
Streptomyces
VITSTK7 sp. against the larvae of
H
.
bispinosa
(LC
50
= 1,573.36, 1,333.09, 1,073.29, and 409.71 ppm;
r
2
= 0.0.990, 0.934, 0.935, and 0.908),
R. microplus
(LC
50
= 1,877.86, 815.83, 1,631.14, and 441.54 ppm;
r
2
= 0.981, 0.926, 0.0970, and 0.915),
A. subpictus
(LC
50
= 273.89, 687.69, 464.75, and 223.83 ppm;
r
2
= 0.758, 0.924, 0.841, and 0.902), and
C
.
quinquefasciatus
(LC
50
= 430.06, 881.59, 777.0, and 195.70 ppm;
r
2
= 0.839, 0.859, 0.870, and 0.882), respectively. Results of the present study provide evidence that the maximum parasitic activity of ethyl acetate extract and a synergistic effect of combinations of different compounds have been suggested. The control (distilled water) showed nil mortality in the concurrent assay. In the present study, a novel, targeted, simple, and eco-friendly approach has been suggested to control blood-feeding parasites.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>23180127</pmid><doi>10.1007/s00436-012-3192-3</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0932-0113 |
| ispartof | Parasitology research (1987), 2013-02, Vol.112 (2), p.719-729 |
| issn | 0932-0113 1432-1955 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1430859745 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Acari Acaricides - chemistry Acaricides - isolation & purification Acaricides - pharmacology Actinobacteria Actinomycetes Animals Anopheles - drug effects Anopheles subpictus Arthropoda Biological Assay Biological control Biological Products - chemistry Biological Products - isolation & purification Biological Products - pharmacology Biomedical and Life Sciences Biomedicine Boophilus microplus Chromatography Control Culex - drug effects Culex quinquefasciatus Culicidae Diptera Environmental aspects Haemaphysalis Health aspects Immunology Insecticides - chemistry Insecticides - isolation & purification Insecticides - pharmacology Ixodidae Ixodidae - drug effects Larva - drug effects Mass Spectrometry Medical Microbiology Microbiology Mosquitoes Original Paper Pests Rhipicephalus Streptomyces Streptomyces - chemistry Streptomyces - isolation & purification Survival Analysis Ticks Water Microbiology |
| title | Eco-friendly approach using marine actinobacteria and its compounds to control ticks and mosquitoes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T08%3A26%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Eco-friendly%20approach%20using%20marine%20actinobacteria%20and%20its%20compounds%20to%20control%20ticks%20and%20mosquitoes&rft.jtitle=Parasitology%20research%20(1987)&rft.au=Thenmozhi,%20Mohankumar&rft.date=2013-02-01&rft.volume=112&rft.issue=2&rft.spage=719&rft.epage=729&rft.pages=719-729&rft.issn=0932-0113&rft.eissn=1432-1955&rft_id=info:doi/10.1007/s00436-012-3192-3&rft_dat=%3Cgale_proqu%3EA336603675%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1430859745&rft_id=info:pmid/23180127&rft_galeid=A336603675&rfr_iscdi=true |