An electrochemical surface plasmon resonance imaging system targeting cell analysis
This paper presents an electrochemical-surface plasmon resonance imaging (EC-SPRI) system, enabling the characterization of optical and electrical properties of cells, simultaneously. The developed surface plasmon resonance (SPR) imaging system was capable of imaging micro cavities with a dimension...
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Veröffentlicht in: | Review of scientific instruments 2013-08, Vol.84 (8), p.085005-085005 |
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creator | Zhang, L L Chen, X Wei, H T Li, H Sun, J H Cai, H Y Chen, J L Cui, D F |
description | This paper presents an electrochemical-surface plasmon resonance imaging (EC-SPRI) system, enabling the characterization of optical and electrical properties of cells, simultaneously. The developed surface plasmon resonance (SPR) imaging system was capable of imaging micro cavities with a dimension of 10 μm × 10 μm and differentiated glycerol solutions with a group of refractive indices (RIs). Furthermore, the EC-SPRI system was used to image A549 cells, suggesting corresponding RI and morphology changes during the cell death process. In the end, electrochemical and SPR methods were used in combination, recording oxidation peaks of A549 cells in the cyclic voltage curves and SPR response unit increase, simultaneously. |
doi_str_mv | 10.1063/1.4819027 |
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The developed surface plasmon resonance (SPR) imaging system was capable of imaging micro cavities with a dimension of 10 μm × 10 μm and differentiated glycerol solutions with a group of refractive indices (RIs). Furthermore, the EC-SPRI system was used to image A549 cells, suggesting corresponding RI and morphology changes during the cell death process. 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In the end, electrochemical and SPR methods were used in combination, recording oxidation peaks of A549 cells in the cyclic voltage curves and SPR response unit increase, simultaneously.</description><subject>Cell Line</subject><subject>Electrochemistry - methods</subject><subject>Humans</subject><subject>Molecular Imaging - methods</subject><subject>Optical Phenomena</subject><subject>Surface Plasmon Resonance - methods</subject><subject>Time Factors</subject><issn>0034-6748</issn><issn>1089-7623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1Lw0AQhhdRbK0e_AOSox5SZz-a3RxL8QsKHtRz2E4mNZJs6k5y6L83xepcBl4eXmYeIa4lzCVk-l7OjZM5KHsiphJcntpM6VMxBdAmzaxxE3HB_AXjLKQ8FxNlAKwEmIq3ZUioIexjh5_U1uibhIdYeaRk13huu5BE4i74MCZ167d12Ca8557apPdxS_0hQGqaxAff7LnmS3FW-Ybp6rhn4uPx4X31nK5fn15Wy3WKeiH7NHdGZVqp0jpCl1lbepTVQildbTYGbZYbXUqHWCEC-qx02gNQLq12hkypZ-L2t3cXu--BuC_amg-X-EDdwIU0GpyxoNWI3v2iGDvmSFWxi-MzcV9IKA4OC1kcHY7szbF22LRU_pN_0vQPOp5r5g</recordid><startdate>201308</startdate><enddate>201308</enddate><creator>Zhang, L L</creator><creator>Chen, X</creator><creator>Wei, H T</creator><creator>Li, H</creator><creator>Sun, J H</creator><creator>Cai, H Y</creator><creator>Chen, J L</creator><creator>Cui, D F</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201308</creationdate><title>An electrochemical surface plasmon resonance imaging system targeting cell analysis</title><author>Zhang, L L ; Chen, X ; Wei, H T ; Li, H ; Sun, J H ; Cai, H Y ; Chen, J L ; Cui, D F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c351t-98426322d78ec8677dac1f5223fbb4c76943d18ccfcc0ca6d83a00e917384e4d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Cell Line</topic><topic>Electrochemistry - methods</topic><topic>Humans</topic><topic>Molecular Imaging - methods</topic><topic>Optical Phenomena</topic><topic>Surface Plasmon Resonance - methods</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, L L</creatorcontrib><creatorcontrib>Chen, X</creatorcontrib><creatorcontrib>Wei, H T</creatorcontrib><creatorcontrib>Li, H</creatorcontrib><creatorcontrib>Sun, J H</creatorcontrib><creatorcontrib>Cai, H Y</creatorcontrib><creatorcontrib>Chen, J L</creatorcontrib><creatorcontrib>Cui, D F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Review of scientific instruments</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, L L</au><au>Chen, X</au><au>Wei, H T</au><au>Li, H</au><au>Sun, J H</au><au>Cai, H Y</au><au>Chen, J L</au><au>Cui, D F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An electrochemical surface plasmon resonance imaging system targeting cell analysis</atitle><jtitle>Review of scientific instruments</jtitle><addtitle>Rev Sci Instrum</addtitle><date>2013-08</date><risdate>2013</risdate><volume>84</volume><issue>8</issue><spage>085005</spage><epage>085005</epage><pages>085005-085005</pages><issn>0034-6748</issn><eissn>1089-7623</eissn><abstract>This paper presents an electrochemical-surface plasmon resonance imaging (EC-SPRI) system, enabling the characterization of optical and electrical properties of cells, simultaneously. 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subjects | Cell Line Electrochemistry - methods Humans Molecular Imaging - methods Optical Phenomena Surface Plasmon Resonance - methods Time Factors |
title | An electrochemical surface plasmon resonance imaging system targeting cell analysis |
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