An electrochemical surface plasmon resonance imaging system targeting cell analysis

This paper presents an electrochemical-surface plasmon resonance imaging (EC-SPRI) system, enabling the characterization of optical and electrical properties of cells, simultaneously. The developed surface plasmon resonance (SPR) imaging system was capable of imaging micro cavities with a dimension...

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Veröffentlicht in:Review of scientific instruments 2013-08, Vol.84 (8), p.085005-085005
Hauptverfasser: Zhang, L L, Chen, X, Wei, H T, Li, H, Sun, J H, Cai, H Y, Chen, J L, Cui, D F
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container_issue 8
container_start_page 085005
container_title Review of scientific instruments
container_volume 84
creator Zhang, L L
Chen, X
Wei, H T
Li, H
Sun, J H
Cai, H Y
Chen, J L
Cui, D F
description This paper presents an electrochemical-surface plasmon resonance imaging (EC-SPRI) system, enabling the characterization of optical and electrical properties of cells, simultaneously. The developed surface plasmon resonance (SPR) imaging system was capable of imaging micro cavities with a dimension of 10 μm × 10 μm and differentiated glycerol solutions with a group of refractive indices (RIs). Furthermore, the EC-SPRI system was used to image A549 cells, suggesting corresponding RI and morphology changes during the cell death process. In the end, electrochemical and SPR methods were used in combination, recording oxidation peaks of A549 cells in the cyclic voltage curves and SPR response unit increase, simultaneously.
doi_str_mv 10.1063/1.4819027
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subjects Cell Line
Electrochemistry - methods
Humans
Molecular Imaging - methods
Optical Phenomena
Surface Plasmon Resonance - methods
Time Factors
title An electrochemical surface plasmon resonance imaging system targeting cell analysis
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