Management of childhood urticaria: current knowledge and practical recommendations
Urticaria, defined by the presence of wheals and/or angio-edema, is a common condition in children, prompting parents to consult physicians. For its successful management, paediatric-specific features must be taken into account, regarding the identification of eliciting triggers and pharmacological...
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Veröffentlicht in: | Acta dermato-venereologica 2013-01, Vol.93 (5), p.500-508 |
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creator | Pite, Helene Wedi, Bettina Borrego, Luís Miguel Kapp, Alexander Raap, Ulrike |
description | Urticaria, defined by the presence of wheals and/or angio-edema, is a common condition in children, prompting parents to consult physicians. For its successful management, paediatric-specific features must be taken into account, regarding the identification of eliciting triggers and pharmacological therapy. This review systematically discusses the current best-available evidence on spontaneous acute and chronic urticaria as well as physical and other urticaria types in children. Potential underlying causes, namely infections, food and drug hypersensitivity, autoreactivity and autoimmune or other conditions, and eliciting stimuli are considered, with practical recommendations for specific diagnostic approaches. Second-generation antihistamines are the mainstay of pharmacological treatment aimed at relief of symptoms, which require dose adjustment for pae-diatric use. Other therapeutic interventions are also discussed. In addition, unmet needs are highlighted, aiming to promote research into the paediatric population, ultimately aiming at the effective management of childhood urticaria. |
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subjects | Acute Disease Adolescent Age Factors Child Child, Preschool Chronic Disease Drug Dosage Calculations Histamine Antagonists - administration & dosage Histamine Antagonists - adverse effects Humans Infant Practice Guidelines as Topic Risk Factors Treatment Outcome Urticaria - diagnosis Urticaria - drug therapy Urticaria - etiology |
title | Management of childhood urticaria: current knowledge and practical recommendations |
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