Use of a Comprehensive Polymerase Chain Reaction System for Diagnosis of Ocular Infectious Diseases

Purpose To measure the genomic DNA of ocular infectious pathogens in ocular fluids and to analyze the clinical relevance of these pathogens in uveitis and endophthalmitis. Design Prospective clinical case series. Participants A total of 500 patients with infectious uveitis and endophthalmitis were e...

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Veröffentlicht in:	Ophthalmology (Rochester, Minn.) Minn.), 2013-09, Vol.120 (9), p.1761-1768
Hauptverfasser:	Sugita, Sunao, MD, PhD, Ogawa, Manabu, MD, PhD, Shimizu, Norio, PhD, Morio, Tomohiro, MD, PhD, Ohguro, Nobuyuki, MD, PhD, Nakai, Kei, MD, PhD, Maruyama, Kazuichi, MD, PhD, Nagata, Kenji, MD, Takeda, Atsunobu, MD, PhD, Usui, Yoshihiko, MD, PhD, Sonoda, Koh-Hei, MD, PhD, Takeuchi, Masaru, MD, PhD, Mochizuki, Manabu, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA, Bacterial - genetics DNA, Fungal - genetics DNA, Protozoan - genetics DNA, Ribosomal - genetics DNA, Viral - genetics Endophthalmitis - diagnosis Endophthalmitis - microbiology Endophthalmitis - parasitology Endophthalmitis - virology Eye Infections - diagnosis Eye Infections - microbiology Eye Infections - parasitology Eye Infections - virology False Positive Reactions Humans Multiplex Polymerase Chain Reaction - methods Ophthalmology Predictive Value of Tests Prospective Studies Real-Time Polymerase Chain Reaction - methods Reproducibility of Results RNA, Ribosomal, 18S - genetics RNA, Ribosomal, 28S - genetics Sensitivity and Specificity Simplexvirus - genetics Toxoplasma - genetics Uveitis - diagnosis Uveitis - microbiology Uveitis - parasitology Uveitis - virology
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