Identification and bioinformatics analysis of pseudogenes from whole genome sequence of Phaeodactylum tricornutum
Pseudogenes share sequence similarities with functional genes, but in general they have lost their protein-coding ability. The identification of pseudogenes is a very important step in genome annotation. Phaeodactylum tricornutum is a marine diatom that is rich in polyunsaturated fatty acids （PUFAs）...
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| Veröffentlicht in: | Chinese science bulletin 2013-03, Vol.58 (9), p.1010-1017 |
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| creator | Ji, ChangMian Huang, AiYou Liu, WenLing Pan, GuangHua Wang, GuangCe |
| description | Pseudogenes share sequence similarities with functional genes, but in general they have lost their protein-coding ability. The identification of pseudogenes is a very important step in genome annotation. Phaeodactylum tricornutum is a marine diatom that is rich in polyunsaturated fatty acids （PUFAs）. The genome of P. tricornutum has been completely sequenced. To identify pseudogenes in P. tricornutum, we developed a pipeline to discover and characterize pseudogenes. We identified a total of 1654 ＇true＇ processed pseudogenes, 714 duplicated pseudogenes and 4729 pseudogene fragments. The results of the bioinformatics analysis indicated that the genome sequence of P. tricornutum contained many pseudogenes and pseudogene fragments. |
| doi_str_mv | 10.1007/s11434-012-5174-3 |
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The identification of pseudogenes is a very important step in genome annotation. Phaeodactylum tricornutum is a marine diatom that is rich in polyunsaturated fatty acids （PUFAs）. The genome of P. tricornutum has been completely sequenced. To identify pseudogenes in P. tricornutum, we developed a pipeline to discover and characterize pseudogenes. We identified a total of 1654 ＇true＇ processed pseudogenes, 714 duplicated pseudogenes and 4729 pseudogene fragments. 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| subjects | Bacillariophyceae Chemistry/Food Science Earth Sciences Engineering Humanities and Social Sciences Life Sciences multidisciplinary nucleotide sequences Phaeodactylum tricornutum Physics polyunsaturated fatty acids pseudogenes Science Science (multidisciplinary) 三角褐指藻 全基因组序列 基因片段 多不饱和脂肪酸 学分 序列相似性 生物信息 鉴定 |
| title | Identification and bioinformatics analysis of pseudogenes from whole genome sequence of Phaeodactylum tricornutum |
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