Expression levels of PEPT1 and ABCG2 play key roles in 5-aminolevulinic acid (ALA)-induced tumor-specific protoporphyrin IX (PpIX) accumulation in bladder cancer

Summary Background A detection method widely used of late in cancer surgery is 5-aminolevulinic acid-based photodynamic diagnosis (ALA-PDD), which relies on the tumor-specific accumulation of photosensitizing protoporphyrin IX (PpIX) after the administration of ALA. In this regard, we recently repor...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Photodiagnosis and photodynamic therapy 2013-09, Vol.10 (3), p.288-295
Hauptverfasser:	Hagiya, Yuichiro, Fukuhara, Hideo, Matsumoto, Kentaro, Endo, Yoshio, Nakajima, Motowo, Tanaka, Tohru, Okura, Ichiro, Kurabayashi, Atsushi, Furihata, Mutsuo, Inoue, Keiji, Shuin, Taro, Ogura, Shun-ichiro, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Aminolevulinic acid ABCG2 Aminolevulinic Acid - administration & dosage ATP Binding Cassette Transporter, Sub-Family G, Member 2 ATP-Binding Cassette Transporters - metabolism Bladder cancer Drug Therapy, Combination - methods Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - radiation effects Hematology, Oncology and Palliative Medicine Humans Internal Medicine Metabolic Clearance Rate - drug effects Metabolic Clearance Rate - radiation effects Neoplasm Proteins - metabolism PEPT1 Peptide Transporter 1 Photochemotherapy - methods Photodynamic diagnosis Photosensitizing Agents - administration & dosage Protoporphyrin IX Protoporphyrins - pharmacokinetics Signal Transduction - drug effects Signal Transduction - radiation effects Symporters - metabolism Tumor Cells, Cultured Urinary Bladder Neoplasms - drug therapy Urinary Bladder Neoplasms - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!