Anoxia inhibits biofilm development and modulates antibiotic activity

Abstract Background Many infections involve bacterial biofilms that are notoriously antibiotic resistant. Unfortunately, the mechanism for this resistance is unclear. We tested the effect of oxygen concentration on development of Staphylococcus aureus biofilms, and on the ability of gentamicin and v...

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Veröffentlicht in:	The Journal of surgical research 2013-09, Vol.184 (1), p.488-494
Hauptverfasser:	Hess, Donavon J., MD, PhD, Henry-Stanley, Michelle J., PhD, Lusczek, Elizabeth R., PhD, Beilman, Gregory J., MD, Wells, Carol L., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaerobiosis - physiology Anoxia Anti-Bacterial Agents - pharmacology Biofilm Biofilms - drug effects Biofilms - growth & development Drug Resistance, Bacterial - physiology Equipment Contamination Gentamicin Gentamicins - pharmacology Metabolomics Normoxia Oxygen - pharmacology Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - growth & development Staphylococcus aureus - metabolism Surgery Sutures Vancomycin Vancomycin - pharmacology
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