Recombinant bovine S100A8 and A9 enhance IL-1β secretion of interferon-gamma primed monocytes

Calgranulin A (S100A8) and B (S100A9) are found at high levels in inflamed tissue and have been associated with acute and chronic inflammatory disorders. Calgranulins are discussed as damage-associated molecular patterns (DAMPs). To analyze the role of calgranulins for inflammatory responses, bovine...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2013-09, Vol.155 (3), p.162-170
Hauptverfasser:	Koy, Mirja, Hambruch, Nina, Hussen, Jamal, Pfarrer, Christiane, Seyfert, Hans-Martin, Schuberth, Hans-Joachim
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calgranulin A - physiology Calgranulin B - physiology Cattle DAMP HEK293 Cells Humans Inflammasome Interferon-gamma - pharmacology Interleukin-1beta - secretion Lipopolysaccharides - pharmacology Monocytes - immunology Monocytes - secretion Recombinant Proteins - pharmacology S100 Toll-Like Receptor 4 - physiology
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