Starch-based microspheres for sustained-release of curcumin: Preparation and cytotoxic effect on tumor cells

•Original starch-based microspheres were developed for controlled delivery of the antitumor drug curcumin.•The fraction released of curcumin is dependent on pH.•The release mechanism was found to be governed by anomalous transport.•Curcumin-loaded microspheres showed higher toxicity toward Caco-2 an...

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Veröffentlicht in:Carbohydrate polymers 2013-10, Vol.98 (1), p.711-720
Hauptverfasser: Pereira, Antonio G.B., Fajardo, André R., Nocchi, Samara, Nakamura, Celso V., Rubira, Adley F., Muniz, Edvani C.
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Sprache:eng
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