Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content
It is well known that ingestion of a protein source is effective in stimulating muscle protein synthesis after exercise. In addition, there are numerous reports on the impact of leucine and leucine-rich whey protein on muscle protein synthesis and mammalian target of rapamycin (mTOR) signalling. How...
Gespeichert in:
| Veröffentlicht in: | British journal of nutrition 2013-09, Vol.110 (6), p.981-987 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 987 |
|---|---|
| container_issue | 6 |
| container_start_page | 981 |
| container_title | British journal of nutrition |
| container_volume | 110 |
| creator | Kanda, Atsushi Nakayama, Kyosuke Fukasawa, Tomoyuki Koga, Jinichiro Kanegae, Minoru Kawanaka, Kentaro Higuchi, Mitsuru |
| description | It is well known that ingestion of a protein source is effective in stimulating muscle protein synthesis after exercise. In addition, there are numerous reports on the impact of leucine and leucine-rich whey protein on muscle protein synthesis and mammalian target of rapamycin (mTOR) signalling. However, there is only limited information on the effects of whey protein hydrolysates (WPH) on muscle protein synthesis and mTOR signalling. The aim of the present study was to compare the effects of WPH and amino acids on muscle protein synthesis and the initiation of translation in skeletal muscle during the post-exercise phase. Male Sprague–Dawley rats swam for 2 h to depress muscle protein synthesis. Immediately after exercise, the animals were administered either carbohydrate (CHO), CHO plus an amino acid mixture (AA) or CHO plus WPH. At 1 h after exercise, the supplements containing whey-based protein (AA and WPH) caused a significant increase in the fractional rate of protein synthesis (FSR) compared with CHO. WPH also caused a significant increase in FSR compared with AA. Post-exercise ingestion of WPH caused a significant increase in the phosphorylation of mTOR levels compared with AA or CHO. In addition, WPH caused greater phosphorylation of ribosomal protein S6 kinase and eukaryotic initiation factor 4E-binding protein 1 than AA and CHO. In contrast, there was no difference in plasma amino acid levels following supplementation with either AA or WPH. These results indicate that WPH may include active components that are superior to amino acids for stimulating muscle protein synthesis and initiating translation. |
| doi_str_mv | 10.1017/S0007114512006174 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1429216894</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_S0007114512006174</cupid><sourcerecordid>3127202991</sourcerecordid><originalsourceid>FETCH-LOGICAL-c512t-dfca6702f53b81596e770495712da4daffc08cc2bfe71f2a2a6f0a808326810f3</originalsourceid><addsrcrecordid>eNp1kcuKFTEQhoMoznH0AdxIQAQ3rUn6kvRSBm8woKCum5x0ZU6G7uSYSqP9IL6v1cxxFMVVkqqv_vorxdhjKV5IIfXLT0IILWXTSiVEJ3Vzh-1ko9tKdZ26y3ZbutryZ-wB4jU9jRT9fXam6tqYRrY79uNjwlLBd8guIPBvB1j5MacCIfLDOuY0rWgLcFyOxwlmiMWWkCIPcVwcILf8KgMBmSKObqRBlfOCboJbIVxjOQAG5OVgqbYgdyliCWUhQW7nEBO3LoxbuFDoIbvn7YTw6HSesy9vXn--eFddfnj7_uLVZeVo5FKN3tlOC-Xbem9k23egtWj6Vks12ma03jthnFN7D1p6ZZXtvLBGmFp19BO-PmfPb3TJ6dcFsAxzQAfTZCOkBQfZqF7JzvQNoU__Qq_TkiO5I6o17eZDEyVvKJcTYgY_HHOYbV4HKYZtZ8M_O6OaJyflZT_DeFvxa0kEPDsBFp2dfLaRlvWb05pmNhtXn5rbeZ_DeAV_ePxv-5_HsrDp</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1458567027</pqid></control><display><type>article</type><title>Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Free Full-Text Journals in Chemistry</source><source>Cambridge University Press Journals Complete</source><creator>Kanda, Atsushi ; Nakayama, Kyosuke ; Fukasawa, Tomoyuki ; Koga, Jinichiro ; Kanegae, Minoru ; Kawanaka, Kentaro ; Higuchi, Mitsuru</creator><creatorcontrib>Kanda, Atsushi ; Nakayama, Kyosuke ; Fukasawa, Tomoyuki ; Koga, Jinichiro ; Kanegae, Minoru ; Kawanaka, Kentaro ; Higuchi, Mitsuru</creatorcontrib><description>It is well known that ingestion of a protein source is effective in stimulating muscle protein synthesis after exercise. In addition, there are numerous reports on the impact of leucine and leucine-rich whey protein on muscle protein synthesis and mammalian target of rapamycin (mTOR) signalling. However, there is only limited information on the effects of whey protein hydrolysates (WPH) on muscle protein synthesis and mTOR signalling. The aim of the present study was to compare the effects of WPH and amino acids on muscle protein synthesis and the initiation of translation in skeletal muscle during the post-exercise phase. Male Sprague–Dawley rats swam for 2 h to depress muscle protein synthesis. Immediately after exercise, the animals were administered either carbohydrate (CHO), CHO plus an amino acid mixture (AA) or CHO plus WPH. At 1 h after exercise, the supplements containing whey-based protein (AA and WPH) caused a significant increase in the fractional rate of protein synthesis (FSR) compared with CHO. WPH also caused a significant increase in FSR compared with AA. Post-exercise ingestion of WPH caused a significant increase in the phosphorylation of mTOR levels compared with AA or CHO. In addition, WPH caused greater phosphorylation of ribosomal protein S6 kinase and eukaryotic initiation factor 4E-binding protein 1 than AA and CHO. In contrast, there was no difference in plasma amino acid levels following supplementation with either AA or WPH. These results indicate that WPH may include active components that are superior to amino acids for stimulating muscle protein synthesis and initiating translation.</description><identifier>ISSN: 0007-1145</identifier><identifier>EISSN: 1475-2662</identifier><identifier>DOI: 10.1017/S0007114512006174</identifier><identifier>PMID: 23388415</identifier><identifier>CODEN: BJNUAV</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Amino acids ; Amino Acids - blood ; Amino Acids - chemistry ; Amino Acids - pharmacology ; Animals ; Biological and medical sciences ; Carrier Proteins - genetics ; Carrier Proteins - metabolism ; Dietary Supplements ; Exercise ; Feeding. Feeding behavior ; Fundamental and applied biological sciences. Psychology ; Gene Expression Regulation - drug effects ; Ingestion ; Insulin - blood ; Male ; Metabolism and Metabolic Studies ; Milk Proteins - administration & dosage ; Milk Proteins - pharmacology ; Muscle Proteins - genetics ; Muscle Proteins - metabolism ; Muscle, Skeletal - physiology ; Muscular system ; Phosphoproteins - genetics ; Phosphoproteins - metabolism ; Phosphorylation ; Physical Conditioning, Animal - physiology ; Protein synthesis ; Proteins ; Rats ; Rats, Sprague-Dawley ; Ribosomal Protein S6 Kinases - genetics ; Ribosomal Protein S6 Kinases - metabolism ; Rodents ; Swimming - physiology ; TOR Serine-Threonine Kinases ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Whey Proteins</subject><ispartof>British journal of nutrition, 2013-09, Vol.110 (6), p.981-987</ispartof><rights>Copyright © The Authors 2013</rights><rights>2014 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c512t-dfca6702f53b81596e770495712da4daffc08cc2bfe71f2a2a6f0a808326810f3</citedby><cites>FETCH-LOGICAL-c512t-dfca6702f53b81596e770495712da4daffc08cc2bfe71f2a2a6f0a808326810f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0007114512006174/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,27901,27902,55603</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27749585$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23388415$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kanda, Atsushi</creatorcontrib><creatorcontrib>Nakayama, Kyosuke</creatorcontrib><creatorcontrib>Fukasawa, Tomoyuki</creatorcontrib><creatorcontrib>Koga, Jinichiro</creatorcontrib><creatorcontrib>Kanegae, Minoru</creatorcontrib><creatorcontrib>Kawanaka, Kentaro</creatorcontrib><creatorcontrib>Higuchi, Mitsuru</creatorcontrib><title>Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content</title><title>British journal of nutrition</title><addtitle>Br J Nutr</addtitle><description>It is well known that ingestion of a protein source is effective in stimulating muscle protein synthesis after exercise. In addition, there are numerous reports on the impact of leucine and leucine-rich whey protein on muscle protein synthesis and mammalian target of rapamycin (mTOR) signalling. However, there is only limited information on the effects of whey protein hydrolysates (WPH) on muscle protein synthesis and mTOR signalling. The aim of the present study was to compare the effects of WPH and amino acids on muscle protein synthesis and the initiation of translation in skeletal muscle during the post-exercise phase. Male Sprague–Dawley rats swam for 2 h to depress muscle protein synthesis. Immediately after exercise, the animals were administered either carbohydrate (CHO), CHO plus an amino acid mixture (AA) or CHO plus WPH. At 1 h after exercise, the supplements containing whey-based protein (AA and WPH) caused a significant increase in the fractional rate of protein synthesis (FSR) compared with CHO. WPH also caused a significant increase in FSR compared with AA. Post-exercise ingestion of WPH caused a significant increase in the phosphorylation of mTOR levels compared with AA or CHO. In addition, WPH caused greater phosphorylation of ribosomal protein S6 kinase and eukaryotic initiation factor 4E-binding protein 1 than AA and CHO. In contrast, there was no difference in plasma amino acid levels following supplementation with either AA or WPH. These results indicate that WPH may include active components that are superior to amino acids for stimulating muscle protein synthesis and initiating translation.</description><subject>Amino acids</subject><subject>Amino Acids - blood</subject><subject>Amino Acids - chemistry</subject><subject>Amino Acids - pharmacology</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Carrier Proteins - genetics</subject><subject>Carrier Proteins - metabolism</subject><subject>Dietary Supplements</subject><subject>Exercise</subject><subject>Feeding. Feeding behavior</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene Expression Regulation - drug effects</subject><subject>Ingestion</subject><subject>Insulin - blood</subject><subject>Male</subject><subject>Metabolism and Metabolic Studies</subject><subject>Milk Proteins - administration & dosage</subject><subject>Milk Proteins - pharmacology</subject><subject>Muscle Proteins - genetics</subject><subject>Muscle Proteins - metabolism</subject><subject>Muscle, Skeletal - physiology</subject><subject>Muscular system</subject><subject>Phosphoproteins - genetics</subject><subject>Phosphoproteins - metabolism</subject><subject>Phosphorylation</subject><subject>Physical Conditioning, Animal - physiology</subject><subject>Protein synthesis</subject><subject>Proteins</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Ribosomal Protein S6 Kinases - genetics</subject><subject>Ribosomal Protein S6 Kinases - metabolism</subject><subject>Rodents</subject><subject>Swimming - physiology</subject><subject>TOR Serine-Threonine Kinases</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Whey Proteins</subject><issn>0007-1145</issn><issn>1475-2662</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kcuKFTEQhoMoznH0AdxIQAQ3rUn6kvRSBm8woKCum5x0ZU6G7uSYSqP9IL6v1cxxFMVVkqqv_vorxdhjKV5IIfXLT0IILWXTSiVEJ3Vzh-1ko9tKdZ26y3ZbutryZ-wB4jU9jRT9fXam6tqYRrY79uNjwlLBd8guIPBvB1j5MacCIfLDOuY0rWgLcFyOxwlmiMWWkCIPcVwcILf8KgMBmSKObqRBlfOCboJbIVxjOQAG5OVgqbYgdyliCWUhQW7nEBO3LoxbuFDoIbvn7YTw6HSesy9vXn--eFddfnj7_uLVZeVo5FKN3tlOC-Xbem9k23egtWj6Vks12ma03jthnFN7D1p6ZZXtvLBGmFp19BO-PmfPb3TJ6dcFsAxzQAfTZCOkBQfZqF7JzvQNoU__Qq_TkiO5I6o17eZDEyVvKJcTYgY_HHOYbV4HKYZtZ8M_O6OaJyflZT_DeFvxa0kEPDsBFp2dfLaRlvWb05pmNhtXn5rbeZ_DeAV_ePxv-5_HsrDp</recordid><startdate>20130928</startdate><enddate>20130928</enddate><creator>Kanda, Atsushi</creator><creator>Nakayama, Kyosuke</creator><creator>Fukasawa, Tomoyuki</creator><creator>Koga, Jinichiro</creator><creator>Kanegae, Minoru</creator><creator>Kawanaka, Kentaro</creator><creator>Higuchi, Mitsuru</creator><general>Cambridge University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7T5</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20130928</creationdate><title>Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content</title><author>Kanda, Atsushi ; Nakayama, Kyosuke ; Fukasawa, Tomoyuki ; Koga, Jinichiro ; Kanegae, Minoru ; Kawanaka, Kentaro ; Higuchi, Mitsuru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c512t-dfca6702f53b81596e770495712da4daffc08cc2bfe71f2a2a6f0a808326810f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Amino acids</topic><topic>Amino Acids - blood</topic><topic>Amino Acids - chemistry</topic><topic>Amino Acids - pharmacology</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Carrier Proteins - genetics</topic><topic>Carrier Proteins - metabolism</topic><topic>Dietary Supplements</topic><topic>Exercise</topic><topic>Feeding. Feeding behavior</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gene Expression Regulation - drug effects</topic><topic>Ingestion</topic><topic>Insulin - blood</topic><topic>Male</topic><topic>Metabolism and Metabolic Studies</topic><topic>Milk Proteins - administration & dosage</topic><topic>Milk Proteins - pharmacology</topic><topic>Muscle Proteins - genetics</topic><topic>Muscle Proteins - metabolism</topic><topic>Muscle, Skeletal - physiology</topic><topic>Muscular system</topic><topic>Phosphoproteins - genetics</topic><topic>Phosphoproteins - metabolism</topic><topic>Phosphorylation</topic><topic>Physical Conditioning, Animal - physiology</topic><topic>Protein synthesis</topic><topic>Proteins</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Ribosomal Protein S6 Kinases - genetics</topic><topic>Ribosomal Protein S6 Kinases - metabolism</topic><topic>Rodents</topic><topic>Swimming - physiology</topic><topic>TOR Serine-Threonine Kinases</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Whey Proteins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kanda, Atsushi</creatorcontrib><creatorcontrib>Nakayama, Kyosuke</creatorcontrib><creatorcontrib>Fukasawa, Tomoyuki</creatorcontrib><creatorcontrib>Koga, Jinichiro</creatorcontrib><creatorcontrib>Kanegae, Minoru</creatorcontrib><creatorcontrib>Kawanaka, Kentaro</creatorcontrib><creatorcontrib>Higuchi, Mitsuru</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kanda, Atsushi</au><au>Nakayama, Kyosuke</au><au>Fukasawa, Tomoyuki</au><au>Koga, Jinichiro</au><au>Kanegae, Minoru</au><au>Kawanaka, Kentaro</au><au>Higuchi, Mitsuru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content</atitle><jtitle>British journal of nutrition</jtitle><addtitle>Br J Nutr</addtitle><date>2013-09-28</date><risdate>2013</risdate><volume>110</volume><issue>6</issue><spage>981</spage><epage>987</epage><pages>981-987</pages><issn>0007-1145</issn><eissn>1475-2662</eissn><coden>BJNUAV</coden><abstract>It is well known that ingestion of a protein source is effective in stimulating muscle protein synthesis after exercise. In addition, there are numerous reports on the impact of leucine and leucine-rich whey protein on muscle protein synthesis and mammalian target of rapamycin (mTOR) signalling. However, there is only limited information on the effects of whey protein hydrolysates (WPH) on muscle protein synthesis and mTOR signalling. The aim of the present study was to compare the effects of WPH and amino acids on muscle protein synthesis and the initiation of translation in skeletal muscle during the post-exercise phase. Male Sprague–Dawley rats swam for 2 h to depress muscle protein synthesis. Immediately after exercise, the animals were administered either carbohydrate (CHO), CHO plus an amino acid mixture (AA) or CHO plus WPH. At 1 h after exercise, the supplements containing whey-based protein (AA and WPH) caused a significant increase in the fractional rate of protein synthesis (FSR) compared with CHO. WPH also caused a significant increase in FSR compared with AA. Post-exercise ingestion of WPH caused a significant increase in the phosphorylation of mTOR levels compared with AA or CHO. In addition, WPH caused greater phosphorylation of ribosomal protein S6 kinase and eukaryotic initiation factor 4E-binding protein 1 than AA and CHO. In contrast, there was no difference in plasma amino acid levels following supplementation with either AA or WPH. These results indicate that WPH may include active components that are superior to amino acids for stimulating muscle protein synthesis and initiating translation.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>23388415</pmid><doi>10.1017/S0007114512006174</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1145 |
| ispartof | British journal of nutrition, 2013-09, Vol.110 (6), p.981-987 |
| issn | 0007-1145 1475-2662 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1429216894 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry; Cambridge University Press Journals Complete |
| subjects | Amino acids Amino Acids - blood Amino Acids - chemistry Amino Acids - pharmacology Animals Biological and medical sciences Carrier Proteins - genetics Carrier Proteins - metabolism Dietary Supplements Exercise Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects Ingestion Insulin - blood Male Metabolism and Metabolic Studies Milk Proteins - administration & dosage Milk Proteins - pharmacology Muscle Proteins - genetics Muscle Proteins - metabolism Muscle, Skeletal - physiology Muscular system Phosphoproteins - genetics Phosphoproteins - metabolism Phosphorylation Physical Conditioning, Animal - physiology Protein synthesis Proteins Rats Rats, Sprague-Dawley Ribosomal Protein S6 Kinases - genetics Ribosomal Protein S6 Kinases - metabolism Rodents Swimming - physiology TOR Serine-Threonine Kinases Vertebrates: anatomy and physiology, studies on body, several organs or systems Whey Proteins |
| title | Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T22%3A55%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Post-exercise%20whey%20protein%20hydrolysate%20supplementation%20induces%20a%20greater%20increase%20in%20muscle%20protein%20synthesis%20than%20its%20constituent%20amino%20acid%20content&rft.jtitle=British%20journal%20of%20nutrition&rft.au=Kanda,%20Atsushi&rft.date=2013-09-28&rft.volume=110&rft.issue=6&rft.spage=981&rft.epage=987&rft.pages=981-987&rft.issn=0007-1145&rft.eissn=1475-2662&rft.coden=BJNUAV&rft_id=info:doi/10.1017/S0007114512006174&rft_dat=%3Cproquest_cross%3E3127202991%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1458567027&rft_id=info:pmid/23388415&rft_cupid=10_1017_S0007114512006174&rfr_iscdi=true |