Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment

Two women with rheumatoid arthritis who had experienced miscarriages became pregnant while they were under etanercept treatment. One stopped etanercept after 3 weeks with increased doses of prednisolone, and the other restarted etanercept at a half doses 3 months later. They delivered a healthy baby...

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Veröffentlicht in:Rheumatology international 2013-09, Vol.33 (9), p.2433-2435
Hauptverfasser: Natsumi, Ikumi, Matsukawa, Yoshihiro, Miyagawa, Kohji, Kodaira, Hitomi, Tanaka, Toshitake, Horikoshi, Akira, Takeuchi, Jin, Takei, Masami, Maejima, Mamoru, Akimoto, Jun
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container_end_page 2435
container_issue 9
container_start_page 2433
container_title Rheumatology international
container_volume 33
creator Natsumi, Ikumi
Matsukawa, Yoshihiro
Miyagawa, Kohji
Kodaira, Hitomi
Tanaka, Toshitake
Horikoshi, Akira
Takeuchi, Jin
Takei, Masami
Maejima, Mamoru
Akimoto, Jun
description Two women with rheumatoid arthritis who had experienced miscarriages became pregnant while they were under etanercept treatment. One stopped etanercept after 3 weeks with increased doses of prednisolone, and the other restarted etanercept at a half doses 3 months later. They delivered a healthy baby at full term, and no problems in both expecting mothers and babies were observed. The use of etanercept in patients with rheumatoid arthritis seemed safe for pregnant mothers and their fetuses.
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subjects Adult
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - drug therapy
Etanercept
Female
Humans
Immunoglobulin G - therapeutic use
Infant, Newborn
Medicine
Medicine & Public Health
Miscarriage
Pregnancy
Pregnancy Complications - drug therapy
Receptors, Tumor Necrosis Factor - therapeutic use
Rheumatology
Short Communication
Tumor Necrosis Factor-alpha - antagonists & inhibitors
Womens history
title Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment
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