Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment
Two women with rheumatoid arthritis who had experienced miscarriages became pregnant while they were under etanercept treatment. One stopped etanercept after 3 weeks with increased doses of prednisolone, and the other restarted etanercept at a half doses 3 months later. They delivered a healthy baby...
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Veröffentlicht in: | Rheumatology international 2013-09, Vol.33 (9), p.2433-2435 |
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container_title | Rheumatology international |
container_volume | 33 |
creator | Natsumi, Ikumi Matsukawa, Yoshihiro Miyagawa, Kohji Kodaira, Hitomi Tanaka, Toshitake Horikoshi, Akira Takeuchi, Jin Takei, Masami Maejima, Mamoru Akimoto, Jun |
description | Two women with rheumatoid arthritis who had experienced miscarriages became pregnant while they were under etanercept treatment. One stopped etanercept after 3 weeks with increased doses of prednisolone, and the other restarted etanercept at a half doses 3 months later. They delivered a healthy baby at full term, and no problems in both expecting mothers and babies were observed. The use of etanercept in patients with rheumatoid arthritis seemed safe for pregnant mothers and their fetuses. |
doi_str_mv | 10.1007/s00296-012-2433-1 |
format | Article |
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One stopped etanercept after 3 weeks with increased doses of prednisolone, and the other restarted etanercept at a half doses 3 months later. They delivered a healthy baby at full term, and no problems in both expecting mothers and babies were observed. 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The use of etanercept in patients with rheumatoid arthritis seemed safe for pregnant mothers and their fetuses.</description><subject>Adult</subject><subject>Antirheumatic Agents - therapeutic use</subject><subject>Arthritis, Rheumatoid - drug therapy</subject><subject>Etanercept</subject><subject>Female</subject><subject>Humans</subject><subject>Immunoglobulin G - therapeutic use</subject><subject>Infant, Newborn</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Miscarriage</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - drug therapy</subject><subject>Receptors, Tumor Necrosis Factor - therapeutic use</subject><subject>Rheumatology</subject><subject>Short Communication</subject><subject>Tumor Necrosis Factor-alpha - antagonists & inhibitors</subject><subject>Womens history</subject><issn>0172-8172</issn><issn>1437-160X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kUFrHSEUhaW0NK9pf0A2Qcimm2m9Ok-dZQhJWwh00Ra6E59zzRhmxld1-si_r8NLQil0oXLlO8eDh5AzYB-AMfUxM8Y72TDgDW-FaOAF2UArVAOS_XxJNgwUb3TdTsibnO9ZnaVkr8kJ51uuoIUN-f1tcQ5z9stI3RDGfoc2hfmOhpmWQ6SHOOFMD6EMNA24TLbE0FObypBCCZnauU50CLnE9ECjp1PIzqYU7B1S6wsmisXOmBzuCy0JbamG5S155e2Y8d3jeUp-3Fx_v_rc3H799OXq8rZxQvHSQOeZELZv-863rOdb3WvplJcSndWd5orveAcIXmDrNOiWa2hZvUSQvdiKU_L-6LtP8deCuZg1H45jjRSXbKAKuOy0EhW9-Ae9j0uaa7qVUmJdslJwpFyKOSf0Zp_CZNODAWbWUsyxFFNLMWspBqrm_NF52U3YPyueWqgAPwJ5v_49pr-e_q_rH_74mAM</recordid><startdate>20130901</startdate><enddate>20130901</enddate><creator>Natsumi, Ikumi</creator><creator>Matsukawa, Yoshihiro</creator><creator>Miyagawa, Kohji</creator><creator>Kodaira, Hitomi</creator><creator>Tanaka, Toshitake</creator><creator>Horikoshi, Akira</creator><creator>Takeuchi, Jin</creator><creator>Takei, Masami</creator><creator>Maejima, Mamoru</creator><creator>Akimoto, Jun</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20130901</creationdate><title>Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment</title><author>Natsumi, Ikumi ; 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subjects | Adult Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - drug therapy Etanercept Female Humans Immunoglobulin G - therapeutic use Infant, Newborn Medicine Medicine & Public Health Miscarriage Pregnancy Pregnancy Complications - drug therapy Receptors, Tumor Necrosis Factor - therapeutic use Rheumatology Short Communication Tumor Necrosis Factor-alpha - antagonists & inhibitors Womens history |
title | Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment |
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