Selection of high efficient transdermal lipid vesicle for curcumin skin delivery

Curcumin shows effective anti-inflammatory activities but is seldom used in clinic because of its poor solubility in water and vulnerablity to sunshine ultraviolet effect. Novel lipid vesicles have been developed as carriers for skin delivery. In this paper, lipid vesicles—propylene glycol liposomes...

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Veröffentlicht in:	International journal of pharmaceutics 2013-09, Vol.454 (1), p.302-309
Hauptverfasser:	Zhao, Ying-Zheng, Lu, Cui-Tao, Zhang, Yi, Xiao, Jian, Zhao, Ya-Ping, Tian, Ji-Lai, Xu, Yan-Yan, Feng, Zhi-Guo, Xu, Chong-Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Animals Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - metabolism Anti-inflammatory effect Carrageenan Chemistry, Pharmaceutical Curcumin Curcumin - administration & dosage Curcumin - chemistry Curcumin - metabolism Delayed-Action Preparations Disease Models, Animal Drug Stability Edema - chemically induced Edema - prevention & control Encapsulation efficiency Female Inflammation - chemically induced Inflammation - prevention & control Kinetics Lipids - chemistry Liposomes Male Particle Size Propylene Glycol - chemistry Rats, Sprague-Dawley Skin - metabolism Skin Absorption Solubility Technology, Pharmaceutical - methods Transdermal vector
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