Endothelin-1 inhibits sodium reabsorption by ET(A) and ET(B) receptors in the mouse cortical collecting duct

The collecting duct (CD) is a major renal site for the hormonal regulation of Na homeostasis and is critical for systemic arterial blood pressure control. Our previous studies demonstrated that the endothelin-1 gene (edn1) is an early response gene to the action of aldosterone. Because aldosterone a...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2013-08, Vol.305 (4), p.F568-F573
Hauptverfasser:	Lynch, I Jeanette, Welch, Amanda K, Kohan, Donald E, Cain, Brian D, Wingo, Charles S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amiloride - analogs & derivatives Amiloride - pharmacology Animals Endothelin-1 - pharmacology Endothelin-1 - physiology Epithelial Sodium Channels - metabolism Female Humans Kidney Tubules, Collecting - drug effects Kidney Tubules, Collecting - metabolism Male Mice Receptor, Endothelin A - metabolism Receptor, Endothelin B - metabolism Sodium - metabolism
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