A permeation method for detection of self-aggregation of doxorubicin in aqueous environment

•A new method for detection of drug aggregation in aqueous solutions is presented.•The number of drug molecules incorporated in the aggregates was estimated.•TEM measurements confirmed formation of aggregates and their size distribution. For pharmaceutical scientists, it is important to know if diss...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of pharmaceutics 2013-09, Vol.454 (1), p.559-561
Hauptverfasser:	Fülöp, Zoltán, Gref, Ruxandra, Loftsson, Thorsteinn
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggregation aqueous solutions Chemistry, Pharmaceutical Dimerization Doxorubicin Doxorubicin - chemistry hydrophobicity Microscopy, Electron, Transmission Models, Chemical oligosaccharides Particle Size Permeability Permeation scientists Self-association Solubility Technology, Pharmaceutical - methods transmission electron microscopy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!