Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry
We developed an X-ray phase imaging system based on Talbot-Lau interferometry and studied its feasibility for clinical diagnoses of joint diseases. The system consists of three X-ray gratings, a conventional X-ray tube, an object holder, an X-ray image sensor, and a computer for image processing. Th...
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| Veröffentlicht in: | Zeitschrift für medizinische Physik 2013-09, Vol.23 (3), p.222-227 |
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| container_title | Zeitschrift für medizinische Physik |
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| creator | Tanaka, Junji Nagashima, Masabumi Kido, Kazuhiro Hoshino, Yoshihide Kiyohara, Junko Makifuchi, Chiho Nishino, Satoshi Nagatsuka, Sumiya Momose, Atsushi |
| description | We developed an X-ray phase imaging system based on Talbot-Lau interferometry and studied its feasibility for clinical diagnoses of joint diseases. The system consists of three X-ray gratings, a conventional X-ray tube, an object holder, an X-ray image sensor, and a computer for image processing. The joints of human cadavers and healthy volunteers were imaged, and the results indicated sufficient sensitivity to cartilage, suggesting medical significance.
Wir entwickelten ein Röntgen-Phasen-Imaging-System, basierend auf Talbot-Lau-Interferometrie und bestehend aus drei Röntgengittern, einer konventionellen Röntgenröhre, einem Objekttisch, einem Röntgenbildsensor und einem Computer zur Bildverarbeitung. Anschließend untersuchten wir seine Nutzbarkeit für die Diagnostizierung von Gelenkerkrankungen, wobei die Gelenke von gesunden Probanden sowie von Verstorbenen dargestellt werden konnten. Die Ergebnisse zeigten eine ausreichende Sensitivität für Knorpel, was für die klinische Bedeutsamkeit unseres entwickelten Systems spricht. |
| doi_str_mv | 10.1016/j.zemedi.2012.11.004 |
| format | Article |
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Wir entwickelten ein Röntgen-Phasen-Imaging-System, basierend auf Talbot-Lau-Interferometrie und bestehend aus drei Röntgengittern, einer konventionellen Röntgenröhre, einem Objekttisch, einem Röntgenbildsensor und einem Computer zur Bildverarbeitung. Anschließend untersuchten wir seine Nutzbarkeit für die Diagnostizierung von Gelenkerkrankungen, wobei die Gelenke von gesunden Probanden sowie von Verstorbenen dargestellt werden konnten. Die Ergebnisse zeigten eine ausreichende Sensitivität für Knorpel, was für die klinische Bedeutsamkeit unseres entwickelten Systems spricht.</description><identifier>ISSN: 0939-3889</identifier><identifier>EISSN: 1876-4436</identifier><identifier>DOI: 10.1016/j.zemedi.2012.11.004</identifier><identifier>PMID: 23219283</identifier><language>eng</language><publisher>Germany: Elsevier GmbH</publisher><subject>a new imaging technology ; Arthrography - instrumentation ; Cadaver ; cadavers and normal volunteers ; Equipment Design ; Equipment Failure Analysis ; Feasibility Studies ; Finger Joint - diagnostic imaging ; Humans ; in vivo imaging ; Interferometry - instrumentation ; neue Röntgentechnik ; Refractometry - instrumentation ; Reproducibility of Results ; Röntgeninterferometrie ; Sensitivity and Specificity ; Tomography, X-Ray Computed - instrumentation ; Verstorbene und gesunde Probanden ; X-Ray Diffraction - instrumentation ; X-ray interferometry</subject><ispartof>Zeitschrift für medizinische Physik, 2013-09, Vol.23 (3), p.222-227</ispartof><rights>2012</rights><rights>Copyright © 2012. Published by Elsevier GmbH.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-a88e49ac5af70344e4c712bb7a417ddc51aa0bef08e55b28ff311ff32af414273</citedby><cites>FETCH-LOGICAL-c474t-a88e49ac5af70344e4c712bb7a417ddc51aa0bef08e55b28ff311ff32af414273</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.zemedi.2012.11.004$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23219283$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tanaka, Junji</creatorcontrib><creatorcontrib>Nagashima, Masabumi</creatorcontrib><creatorcontrib>Kido, Kazuhiro</creatorcontrib><creatorcontrib>Hoshino, Yoshihide</creatorcontrib><creatorcontrib>Kiyohara, Junko</creatorcontrib><creatorcontrib>Makifuchi, Chiho</creatorcontrib><creatorcontrib>Nishino, Satoshi</creatorcontrib><creatorcontrib>Nagatsuka, Sumiya</creatorcontrib><creatorcontrib>Momose, Atsushi</creatorcontrib><title>Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry</title><title>Zeitschrift für medizinische Physik</title><addtitle>Z Med Phys</addtitle><description>We developed an X-ray phase imaging system based on Talbot-Lau interferometry and studied its feasibility for clinical diagnoses of joint diseases. The system consists of three X-ray gratings, a conventional X-ray tube, an object holder, an X-ray image sensor, and a computer for image processing. The joints of human cadavers and healthy volunteers were imaged, and the results indicated sufficient sensitivity to cartilage, suggesting medical significance.
Wir entwickelten ein Röntgen-Phasen-Imaging-System, basierend auf Talbot-Lau-Interferometrie und bestehend aus drei Röntgengittern, einer konventionellen Röntgenröhre, einem Objekttisch, einem Röntgenbildsensor und einem Computer zur Bildverarbeitung. Anschließend untersuchten wir seine Nutzbarkeit für die Diagnostizierung von Gelenkerkrankungen, wobei die Gelenke von gesunden Probanden sowie von Verstorbenen dargestellt werden konnten. Die Ergebnisse zeigten eine ausreichende Sensitivität für Knorpel, was für die klinische Bedeutsamkeit unseres entwickelten Systems spricht.</description><subject>a new imaging technology</subject><subject>Arthrography - instrumentation</subject><subject>Cadaver</subject><subject>cadavers and normal volunteers</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Feasibility Studies</subject><subject>Finger Joint - diagnostic imaging</subject><subject>Humans</subject><subject>in vivo imaging</subject><subject>Interferometry - instrumentation</subject><subject>neue Röntgentechnik</subject><subject>Refractometry - instrumentation</subject><subject>Reproducibility of Results</subject><subject>Röntgeninterferometrie</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, X-Ray Computed - instrumentation</subject><subject>Verstorbene und gesunde Probanden</subject><subject>X-Ray Diffraction - instrumentation</subject><subject>X-ray interferometry</subject><issn>0939-3889</issn><issn>1876-4436</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVoSTZp_0EpOvZiVyPLX5dCWZo0sNBLCr2JsTxOtNjSRpIXtr--Cpv22IsE0vO-wzyMfQBRgoDm8778TQuNtpQCZAlQCqEu2Aa6timUqpo3bCP6qi-qruuv2HWMeyHqFhp5ya5kJaGXXbVhz1sc8UjBGo5u5Nbxoz16_rQu6PjeW5e4XfDRukc-YKSRe8dHO00UyCWLMz885WduvEsBY-LDif8qAp74A86DT8UO11yaKOSEXyiF0zv2dsI50vvX-4b9vP32sP1e7H7c3W-_7gqjWpUK7DpSPZoap1ZUSpEyLchhaFFBO46mBkQx0CQ6qutBdtNUAeRD4qRAyba6YZ_OvYfgn1eKSS82GppndOTXqDMkoBWiqTOqzqgJPsZAkz6EvHU4aRD6Rbbe67Ns_SJbA-gsO8c-vk5Yh_z5L_TXbga-nAHKex4tBR2NJWdyUSCT9Ojt_yf8AXPOk7A</recordid><startdate>201309</startdate><enddate>201309</enddate><creator>Tanaka, Junji</creator><creator>Nagashima, Masabumi</creator><creator>Kido, Kazuhiro</creator><creator>Hoshino, Yoshihide</creator><creator>Kiyohara, Junko</creator><creator>Makifuchi, Chiho</creator><creator>Nishino, Satoshi</creator><creator>Nagatsuka, Sumiya</creator><creator>Momose, Atsushi</creator><general>Elsevier GmbH</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201309</creationdate><title>Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry</title><author>Tanaka, Junji ; Nagashima, Masabumi ; Kido, Kazuhiro ; Hoshino, Yoshihide ; Kiyohara, Junko ; Makifuchi, Chiho ; Nishino, Satoshi ; Nagatsuka, Sumiya ; Momose, Atsushi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-a88e49ac5af70344e4c712bb7a417ddc51aa0bef08e55b28ff311ff32af414273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>a new imaging technology</topic><topic>Arthrography - instrumentation</topic><topic>Cadaver</topic><topic>cadavers and normal volunteers</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Feasibility Studies</topic><topic>Finger Joint - diagnostic imaging</topic><topic>Humans</topic><topic>in vivo imaging</topic><topic>Interferometry - instrumentation</topic><topic>neue Röntgentechnik</topic><topic>Refractometry - instrumentation</topic><topic>Reproducibility of Results</topic><topic>Röntgeninterferometrie</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, X-Ray Computed - instrumentation</topic><topic>Verstorbene und gesunde Probanden</topic><topic>X-Ray Diffraction - instrumentation</topic><topic>X-ray interferometry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tanaka, Junji</creatorcontrib><creatorcontrib>Nagashima, Masabumi</creatorcontrib><creatorcontrib>Kido, Kazuhiro</creatorcontrib><creatorcontrib>Hoshino, Yoshihide</creatorcontrib><creatorcontrib>Kiyohara, Junko</creatorcontrib><creatorcontrib>Makifuchi, Chiho</creatorcontrib><creatorcontrib>Nishino, Satoshi</creatorcontrib><creatorcontrib>Nagatsuka, Sumiya</creatorcontrib><creatorcontrib>Momose, Atsushi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Zeitschrift für medizinische Physik</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tanaka, Junji</au><au>Nagashima, Masabumi</au><au>Kido, Kazuhiro</au><au>Hoshino, Yoshihide</au><au>Kiyohara, Junko</au><au>Makifuchi, Chiho</au><au>Nishino, Satoshi</au><au>Nagatsuka, Sumiya</au><au>Momose, Atsushi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry</atitle><jtitle>Zeitschrift für medizinische Physik</jtitle><addtitle>Z Med Phys</addtitle><date>2013-09</date><risdate>2013</risdate><volume>23</volume><issue>3</issue><spage>222</spage><epage>227</epage><pages>222-227</pages><issn>0939-3889</issn><eissn>1876-4436</eissn><abstract>We developed an X-ray phase imaging system based on Talbot-Lau interferometry and studied its feasibility for clinical diagnoses of joint diseases. The system consists of three X-ray gratings, a conventional X-ray tube, an object holder, an X-ray image sensor, and a computer for image processing. The joints of human cadavers and healthy volunteers were imaged, and the results indicated sufficient sensitivity to cartilage, suggesting medical significance.
Wir entwickelten ein Röntgen-Phasen-Imaging-System, basierend auf Talbot-Lau-Interferometrie und bestehend aus drei Röntgengittern, einer konventionellen Röntgenröhre, einem Objekttisch, einem Röntgenbildsensor und einem Computer zur Bildverarbeitung. Anschließend untersuchten wir seine Nutzbarkeit für die Diagnostizierung von Gelenkerkrankungen, wobei die Gelenke von gesunden Probanden sowie von Verstorbenen dargestellt werden konnten. Die Ergebnisse zeigten eine ausreichende Sensitivität für Knorpel, was für die klinische Bedeutsamkeit unseres entwickelten Systems spricht.</abstract><cop>Germany</cop><pub>Elsevier GmbH</pub><pmid>23219283</pmid><doi>10.1016/j.zemedi.2012.11.004</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | a new imaging technology Arthrography - instrumentation Cadaver cadavers and normal volunteers Equipment Design Equipment Failure Analysis Feasibility Studies Finger Joint - diagnostic imaging Humans in vivo imaging Interferometry - instrumentation neue Röntgentechnik Refractometry - instrumentation Reproducibility of Results Röntgeninterferometrie Sensitivity and Specificity Tomography, X-Ray Computed - instrumentation Verstorbene und gesunde Probanden X-Ray Diffraction - instrumentation X-ray interferometry |
| title | Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry |
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