role of cholinergic anti-inflammatory pathway in acetic acid-induced colonic inflammation in the rat

The “cholinergic anti-inflammatory pathway” provides neurological modulation of cytokine synthesis to limit the magnitude of the immune response. This study aimed to evaluate the impact of the cholinergic anti-inflammatory pathway on the extent of tissue integrity, oxidant-antioxidant status and neu...

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Veröffentlicht in:	Chemico-biological interactions 2013-09, Vol.205 (1), p.72-80
Hauptverfasser:	Kolgazi, Meltem, Uslu, Unal, Yuksel, Meral, Velioglu-Ogunc, Ayliz, Ercan, Feriha, Alican, Inci
Format:	Artikel
Sprache:	eng
Schlagworte:	acetic acid Acetic Acid - toxicity Alkaloids - pharmacology animal models Animals Antioxidants - metabolism blood serum chemiluminescence Cholinergic Neurons - drug effects Cholinergic Neurons - physiology Cholinesterase Inhibitors - pharmacology colitis Colitis - etiology Colitis - immunology Colitis - physiopathology colon Colon - drug effects Colon - metabolism Colon - pathology Cytokines - blood decapitation Female glutathione Glutathione - metabolism immune response immunohistochemistry inflammation interleukin-10 interleukin-1beta Male malondialdehyde Malondialdehyde - metabolism myeloperoxidase Neuroimmunomodulation - drug effects Neuroimmunomodulation - physiology NF-kappa B - metabolism nicotinamide phosphoribosyltransferase Nicotinamide Phosphoribosyltransferase - blood nicotine Nicotine - pharmacology Nicotinic Agonists - pharmacology Peroxidase - metabolism Rats Rats, Sprague-Dawley reactive oxygen species resistin Resistin - blood Sesquiterpenes - pharmacology transcription factor NF-kappa B tumor necrosis factor-alpha
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