Infusion of galanin into the mid-caudal portion of the dorsal raphe nucleus has an anxiolytic effect on rats in the elevated T-maze

•Galanin into the dorsal raphe nucleus impaired avoidance in the elevated T-maze.•Galanin has an anxiolytic effect only into the mid-caudal dorsal raphe nucleus.•A galanin antagonist, M40, attenuated galanin-induced impairment of avoidance. Galanin and 5-HT coexist in dorsal raphe nucleus (DRN) neur...

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Veröffentlicht in:	Behavioural brain research 2013-09, Vol.252, p.312-317
Hauptverfasser:	Silote, Gabriela Pandini, Rosal, Aline Boroto, Souza, Mayara Machado de, Beijamini, Vanessa
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Anti-Anxiety Agents - pharmacology Anti-Anxiety Agents - therapeutic use Anxiety Anxiety - drug therapy Avoidance Learning - drug effects Behavioral psychophysiology Biological and medical sciences Disease Models, Animal Dorsal raphe nucleus Dose-Response Relationship, Drug Elevated T-maze Escape Reaction - drug effects Fundamental and applied biological sciences. Psychology Galanin Galanin - pharmacology Galanin - therapeutic use Male Maze Learning - drug effects Maze Learning - physiology Medical sciences Motor Activity - drug effects Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychopharmacology Raphe Nuclei - drug effects Raphe Nuclei - physiology Rats Rats, Wistar
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