Atrial Fibrillation: Inflammation in Disguise?

Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo‐embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occ...

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Veröffentlicht in:Scandinavian journal of immunology 2013-08, Vol.78 (2), p.112-119
Hauptverfasser: Lappegård, K. T., Hovland, A., Pop, G. A. M., Mollnes, T. E.
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container_end_page 119
container_issue 2
container_start_page 112
container_title Scandinavian journal of immunology
container_volume 78
creator Lappegård, K. T.
Hovland, A.
Pop, G. A. M.
Mollnes, T. E.
description Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo‐embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occurrence of the arrhythmia to dreaded complications such as strokes or peripheral emboli. As the standard drug combination which aims at rate control and anticoagulation only offers partial protection against complications, newer agents are needed to optimize treatment. In this paper, we review recent knowledge regarding the impact of inflammation on the occurrence, recurrence, perpetuation and complications of the arrhythmia, as well as the role of anti‐inflammatory therapies in the treatment for the disease.
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subjects Animals
Anti-Arrhythmia Agents - therapeutic use
Anti-Inflammatory Agents - therapeutic use
Anticoagulants - therapeutic use
Arrhythmias, Cardiac - drug therapy
Arrhythmias, Cardiac - etiology
Arrhythmias, Cardiac - physiopathology
Atrial Fibrillation - complications
Atrial Fibrillation - drug therapy
Atrial Fibrillation - physiopathology
Heart Failure - drug therapy
Heart Failure - etiology
Heart Failure - physiopathology
Humans
Inflammation - drug therapy
Stroke - drug therapy
Stroke - etiology
Stroke - physiopathology
Thromboembolism - drug therapy
Thromboembolism - etiology
Thromboembolism - physiopathology
title Atrial Fibrillation: Inflammation in Disguise?
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