Atrial Fibrillation: Inflammation in Disguise?
Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo‐embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occ...
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Veröffentlicht in: | Scandinavian journal of immunology 2013-08, Vol.78 (2), p.112-119 |
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creator | Lappegård, K. T. Hovland, A. Pop, G. A. M. Mollnes, T. E. |
description | Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo‐embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occurrence of the arrhythmia to dreaded complications such as strokes or peripheral emboli. As the standard drug combination which aims at rate control and anticoagulation only offers partial protection against complications, newer agents are needed to optimize treatment. In this paper, we review recent knowledge regarding the impact of inflammation on the occurrence, recurrence, perpetuation and complications of the arrhythmia, as well as the role of anti‐inflammatory therapies in the treatment for the disease. |
doi_str_mv | 10.1111/sji.12061 |
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T.</creatorcontrib><creatorcontrib>Hovland, A.</creatorcontrib><creatorcontrib>Pop, G. A. M.</creatorcontrib><creatorcontrib>Mollnes, T. E.</creatorcontrib><title>Atrial Fibrillation: Inflammation in Disguise?</title><title>Scandinavian journal of immunology</title><addtitle>Scand J Immunol</addtitle><description>Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo‐embolism. Over the past years, there has been increasing interest in the role of inflammatory processes in atrial fibrillation, from the first occurrence of the arrhythmia to dreaded complications such as strokes or peripheral emboli. As the standard drug combination which aims at rate control and anticoagulation only offers partial protection against complications, newer agents are needed to optimize treatment. 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subjects | Animals Anti-Arrhythmia Agents - therapeutic use Anti-Inflammatory Agents - therapeutic use Anticoagulants - therapeutic use Arrhythmias, Cardiac - drug therapy Arrhythmias, Cardiac - etiology Arrhythmias, Cardiac - physiopathology Atrial Fibrillation - complications Atrial Fibrillation - drug therapy Atrial Fibrillation - physiopathology Heart Failure - drug therapy Heart Failure - etiology Heart Failure - physiopathology Humans Inflammation - drug therapy Stroke - drug therapy Stroke - etiology Stroke - physiopathology Thromboembolism - drug therapy Thromboembolism - etiology Thromboembolism - physiopathology |
title | Atrial Fibrillation: Inflammation in Disguise? |
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