The Role of Microparticles in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus

Microparticles (MPs) are small membrane‐bound vesicles with potent biological activities that can promote the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus (SLE). These particles contain diverse cellular components and are shed from cells during apoptosis or activation. MPs c...

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Veröffentlicht in:	Scandinavian journal of immunology 2013-08, Vol.78 (2), p.140-148
Hauptverfasser:	Dye, J. R., Ullal, A. J., Pisetsky, D. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen-Antibody Complex - metabolism Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - metabolism Arthritis, Rheumatoid - pathology Autoimmunity Biomarkers - metabolism Cell-Derived Microparticles - immunology Cell-Derived Microparticles - metabolism Cell-Derived Microparticles - pathology Complement System Proteins - metabolism Cytokines - immunology Humans Immunologic Factors - metabolism Joints - blood supply Joints - immunology Joints - pathology Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - metabolism Lupus Erythematosus, Systemic - pathology Neovascularization, Pathologic Signal Transduction
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