Culture of human bone marrow-derived mesenchymal stem cells on of poly(l-lactic acid) scaffolds: potential application for the tissue engineering of cartilage

Purpose Due to the attractive properties of poly( l -lactic acid) (PLLA) for tissue engineering, the aim was to determine the growth and differentiation capacity of mesenchymal stromal cells (MSCs) in PLLA scaffolds and their potential use in the treatment of cartilage diseases. Methods MSCs were cu...

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Veröffentlicht in:	Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA sports traumatology, arthroscopy : official journal of the ESSKA, 2013-08, Vol.21 (8), p.1737-1750
Hauptverfasser:	Izal, Iñigo, Aranda, Pablo, Sanz-Ramos, Patricia, Ripalda, Purificación, Mora, Gonzalo, Granero-Moltó, Froilán, Deplaine, Harmony, Gómez-Ribelles, José Luis, Ferrer, Gloria Gallego, Acosta, Victor, Ochoa, Ignacio, García-Aznar, Jose Manuel, Andreu, Enrique J., Monleón-Pradas, Manuel, Doblaré, Manuel, Prósper, Felipe
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adult Aggrecans - metabolism Apoptosis Bone marrow Cartilage Cartilage Diseases - therapy Cell Adhesion Cell Culture Techniques - methods Cell Differentiation Cell Proliferation Cells, Cultured Collagen Type I - metabolism Collagen Type X - metabolism Experimental Study Extracellular Matrix - metabolism Humans Lactic Acid Medicine Medicine & Public Health Mesenchymal Stromal Cells - cytology Microscopy, Electron, Scanning Orthopedics Permeability Polyesters Polymers Stem cells Surgery Tissue engineering Tissue Engineering - methods Tissue Scaffolds
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