Calculations of acute intravenous toxicity in mice based on local regression models in superoverlapping clusters (LRMSC)

Modeling of quantitative structure — activity relationships (QSAR) between physicochemical descriptors of organic chemicals and their acute intravenous toxicity in mice have been presented. This approach includes three steps: structure-similarity chemicals selection for every compound-of-interest (c...

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Veröffentlicht in:	Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry Biomedical chemistry, 2011-12, Vol.5 (4), p.346-356
Hauptverfasser:	Raevsky, O. A., Grigoriev, V. Yu, Liplavskaya, E. A., Worth, A. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioorganic Chemistry Chemistry Chemistry and Materials Science Cluster analysis Medicinal Chemistry Regression analysis Rodents Toxicity
Online-Zugang:	Volltext
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