Red blood cell-derived microparticles isolated from blood units initiate and propagate thrombin generation

Background Red blood cell–derived microparticles (RMPs) are small phospholipid vesicles shed from RBCs in blood units, where they accumulate during storage. Because microparticles are bioactive, it could be suggested that RMPs are mediators of posttransfusion complications or, on the contrary, const...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2013-08, Vol.53 (8), p.1744-1754
Hauptverfasser:	Rubin, Olivier, Delobel, Julien, Prudent, Michel, Lion, Niels, Kohl, Kid, Tucker, Erik I., Tissot, Jean-Daniel, Angelillo-Scherrer, Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Biomarkers - metabolism Blood Blood Coagulation Tests Blood Preservation Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Blotting, Western Cell-Derived Microparticles - physiology Erythrocytes - metabolism Factor XI - metabolism Flow Cytometry Humans Immunohistochemistry Medical research Medical sciences Plasma Plasma - metabolism Thrombin - metabolism Thromboplastin - metabolism Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Online-Zugang:	Volltext
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