Rat kidney brush border enzyme activity following subchronic oral lead exposure

Rats received 0.1% lead acetate in their drinking water for 3 weeks or for 6 weeks, at which time renal brush border fractions were obtained for measurement of enzyme activity. Renal brush border preparations from Pb 2+-exposed rats exhibited statistically significant decreases in the activity of γ-...

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Veröffentlicht in:	Toxicology and applied pharmacology 1985-01, Vol.77 (2), p.211-218
Hauptverfasser:	Teichert-Kuliszewska, Krystyna, Nicholls, D.McEwen
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Alkaline Phosphatase - metabolism Aminopeptidases - antagonists & inhibitors Animals Biological and medical sciences CD13 Antigens Chemical and industrial products toxicology. Toxic occupational diseases gamma-Glutamyltransferase - antagonists & inhibitors Kidney - enzymology Lead - metabolism Lead Poisoning - enzymology Male Medical sciences Membrane Proteins - metabolism Metals and various inorganic compounds Microvilli - enzymology Organometallic Compounds Phospholipids - metabolism Rats Rats, Inbred Strains Toxicology Urokinase-Type Plasminogen Activator - metabolism
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