Neuroprotective properties of the excitatory amino acid carrier 1 (EAAC1)

Extracellular glutamate should be maintained at low levels to conserve optimal neurotransmission and prevent glutamate neurotoxicity in the brain. Excitatory amino acid transporters (EAATs) play a pivotal role in removing extracellular glutamate in the central nervous system (CNS). Excitatory amino...

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Veröffentlicht in:	Amino acids 2013-07, Vol.45 (1), p.133-142
Hauptverfasser:	Aoyama, Koji, Nakaki, Toshio
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid transporters Analytical Chemistry Animals Antioxidants - metabolism Biochemical Engineering Biochemistry Biomedical and Life Sciences brain Central Nervous System - metabolism cysteine Cysteine - metabolism dendrites Excitatory Amino Acid Transporter 3 - metabolism Glutamate Plasma Membrane Transport Proteins - metabolism glutamic acid Glutamic Acid - metabolism glutathione Glutathione - metabolism Humans Life Sciences metabolism Mice Minireview Article Neurobiology neurodegenerative diseases Neuroprotective Agents - metabolism neuroprotective effect neurotoxicity Proteomics Synaptic Transmission
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