Reactivating head regrowth in a regeneration-deficient planarian species

Although the capacity for tissue regeneration of planarians is exceptional, planarians with more limited regenerative capacities are known; here knocking down components of the Wnt signalling pathway rescues head regeneration in the regeneration-impaired planarian Dendrocoelum lacteum , revealing th...

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Veröffentlicht in:	Nature (London) 2013-08, Vol.500 (7460), p.81-84
Hauptverfasser:	Liu, S.-Y., Selck, C., Friedrich, B., Lutz, R., Vila-Farré, M., Dahl, A., Brandl, H., Lakshmanaperumal, N., Henry, I., Rink, J. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136 Amputation Animals beta Catenin - biosynthesis beta Catenin - deficiency beta Catenin - genetics beta Catenin - metabolism Body Patterning Cloning Comparative studies Defects Experiments Genes Genetic engineering Head - growth & development Head - physiology Histology Humanities and Social Sciences Hybridization letter Ligands Models, Animal Molecular Sequence Data multidisciplinary Physiological aspects Planarians - anatomy & histology Planarians - physiology Platyhelminthes Regeneration Regeneration (Biology) Regrowth Science Tail - growth & development Wnt Proteins - metabolism Wnt Signaling Pathway
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