On the use of a single-fiber multipoint plastic scintillation detector for 192Ir high-dose-rate brachytherapy

Purpose: The goal of this study was to prove the feasibility of using a single-fiber multipoint plastic scintillation detector (mPSD) as anin vivo verification tool during 192Ir high-dose-rate brachytherapy treatments. Methods: A three-point detector was built and inserted inside a catheter-position...

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Veröffentlicht in:Medical physics (Lancaster) 2013-06, Vol.40 (6), p.062101-n/a
Hauptverfasser: Therriault-Proulx, François, Beddar, Sam, Beaulieu, Luc
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Beddar, Sam
Beaulieu, Luc
description Purpose: The goal of this study was to prove the feasibility of using a single-fiber multipoint plastic scintillation detector (mPSD) as anin vivo verification tool during 192Ir high-dose-rate brachytherapy treatments. Methods: A three-point detector was built and inserted inside a catheter-positioning template placed in a water phantom. A hyperspectral approach was implemented to discriminate the different optical signals composing the light output at the exit of the single collection optical fiber. The mPSD was tested with different source-to-detector positions, ranging from 1 to 5 cm radially and over 10.5 cm along the longitudinal axis of the detector, and with various integration times. Several strategies for improving the accuracy of the detector were investigated. The device's accuracy in detecting source position was also tested. Results: Good agreement with the expected doses was obtained for all of the scintillating elements, with average relative differences from the expected values of 3.4 ± 2.1%, 3.0 ± 0.7%, and 4.5 ± 1.0% for scintillating elements from the distal to the proximal. A dose threshold of 3 cGy improved the general accuracy of the detector. An integration time of 3 s offered a good trade-off between precision and temporal resolution. Finally, the mPSD measured the radioactive source positioning uncertainty to be no more than 0.32 ± 0.06 mm. The accuracy and precision of the detector were improved by a dose-weighted function combining the three measurement points and known details about the geometry of the detector construction. Conclusions: The use of a mPSD for high-dose-rate brachytherapy dosimetry is feasible. This detector shows great promise for development ofin vivo applications for real-time verification of treatment delivery.
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Methods: A three-point detector was built and inserted inside a catheter-positioning template placed in a water phantom. A hyperspectral approach was implemented to discriminate the different optical signals composing the light output at the exit of the single collection optical fiber. The mPSD was tested with different source-to-detector positions, ranging from 1 to 5 cm radially and over 10.5 cm along the longitudinal axis of the detector, and with various integration times. Several strategies for improving the accuracy of the detector were investigated. The device's accuracy in detecting source position was also tested. Results: Good agreement with the expected doses was obtained for all of the scintillating elements, with average relative differences from the expected values of 3.4 ± 2.1%, 3.0 ± 0.7%, and 4.5 ± 1.0% for scintillating elements from the distal to the proximal. A dose threshold of 3 cGy improved the general accuracy of the detector. An integration time of 3 s offered a good trade-off between precision and temporal resolution. Finally, the mPSD measured the radioactive source positioning uncertainty to be no more than 0.32 ± 0.06 mm. The accuracy and precision of the detector were improved by a dose-weighted function combining the three measurement points and known details about the geometry of the detector construction. Conclusions: The use of a mPSD for high-dose-rate brachytherapy dosimetry is feasible. 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An integration time of 3 s offered a good trade-off between precision and temporal resolution. Finally, the mPSD measured the radioactive source positioning uncertainty to be no more than 0.32 ± 0.06 mm. The accuracy and precision of the detector were improved by a dose-weighted function combining the three measurement points and known details about the geometry of the detector construction. Conclusions: The use of a mPSD for high-dose-rate brachytherapy dosimetry is feasible. This detector shows great promise for development ofin vivo applications for real-time verification of treatment delivery.</description><subject>Biomedical instrumentation and transducers, including micro‐electro‐mechanical systems (MEMS)</subject><subject>brachytherapy</subject><subject>Brachytherapy - instrumentation</subject><subject>Calibration</subject><subject>catheters</subject><subject>Catheters; Hollow probes</subject><subject>dosimetry</subject><subject>Dosimetry/exposure assessment</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Error analysis</subject><subject>Fiber Optic Technology - instrumentation</subject><subject>HDR brachytherapy</subject><subject>Infrared detectors</subject><subject>Infrared sources</subject><subject>Infrared spectra</subject><subject>Iridium Radioisotopes - analysis</subject><subject>Iridium Radioisotopes - therapeutic use</subject><subject>Measurement of nuclear or x‐radiation</subject><subject>multipoint detector</subject><subject>phantoms</subject><subject>plastic scintillation detector</subject><subject>Plastics - radiation effects</subject><subject>Position sensitive detectors</subject><subject>Radiation Measurement Physics</subject><subject>Radiation therapy</subject><subject>Radiotherapy Dosage</subject><subject>Reproducibility of Results</subject><subject>Scintillation Counting - instrumentation</subject><subject>Scintillation detectors</subject><subject>Sensitivity and Specificity</subject><subject>solid scintillation detectors</subject><subject>spectrometry</subject><subject>Therapeutic applications, including brachytherapy</subject><subject>Tubes for determining the presence, intensity, density or energy of radiation or particles</subject><subject>Visible spectra</subject><issn>0094-2405</issn><issn>2473-4209</issn><issn>0094-2405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU2LFDEQhoMo7jh68A9IjiJkTSXpj1wEWVxdWFkPeg7pdDKdpbvTJumV-fdmd8ZhRfBQFEU9VS_1FkKvgZ4DQPsezkVLeQX0Cdow0XAiGJVP0YZSKQgTtDpDL1K6pZTWvKLP0RnjDbSVlBs03cw4DxavyeLgsMbJz7vREuc7G_G0jtkvwc8ZL6NO2RucTKn8OOrsw4x7m63JIWJXAiS7injwu4H0IVkSdba4i9oM-yIR9bJ_iZ45PSb76pi36Mflp-8XX8j1zeeri4_X5JY3lBIHrq20cF3FgFImpJatEVrTcqLu6sb1rq4aw4yTbeM0h76iHKQ2UDfFCcO36MNh77J2k-2NnXPUo1qin3Tcq6C9-rsz-0Htwp3idc3bElv09rgghp-rTVlNPhlbzp5tWJMCAXUtmWBQ0DePtU4ifzwuADkAv_xo96c-UHX_PAXq-Dz19dt9Kvy7A1-szg82n2buQnzEL737H_yPAP8N2ZSoRQ</recordid><startdate>201306</startdate><enddate>201306</enddate><creator>Therriault-Proulx, François</creator><creator>Beddar, Sam</creator><creator>Beaulieu, Luc</creator><general>American Association of Physicists in Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201306</creationdate><title>On the use of a single-fiber multipoint plastic scintillation detector for 192Ir high-dose-rate brachytherapy</title><author>Therriault-Proulx, François ; Beddar, Sam ; Beaulieu, Luc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j3700-f1f85a4fb52100249a98c4aa0510ab67fdf657c2cf987fa31d50319ac167480c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Biomedical instrumentation and transducers, including micro‐electro‐mechanical systems (MEMS)</topic><topic>brachytherapy</topic><topic>Brachytherapy - instrumentation</topic><topic>Calibration</topic><topic>catheters</topic><topic>Catheters; Hollow probes</topic><topic>dosimetry</topic><topic>Dosimetry/exposure assessment</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Error analysis</topic><topic>Fiber Optic Technology - instrumentation</topic><topic>HDR brachytherapy</topic><topic>Infrared detectors</topic><topic>Infrared sources</topic><topic>Infrared spectra</topic><topic>Iridium Radioisotopes - analysis</topic><topic>Iridium Radioisotopes - therapeutic use</topic><topic>Measurement of nuclear or x‐radiation</topic><topic>multipoint detector</topic><topic>phantoms</topic><topic>plastic scintillation detector</topic><topic>Plastics - radiation effects</topic><topic>Position sensitive detectors</topic><topic>Radiation Measurement Physics</topic><topic>Radiation therapy</topic><topic>Radiotherapy Dosage</topic><topic>Reproducibility of Results</topic><topic>Scintillation Counting - instrumentation</topic><topic>Scintillation detectors</topic><topic>Sensitivity and Specificity</topic><topic>solid scintillation detectors</topic><topic>spectrometry</topic><topic>Therapeutic applications, including brachytherapy</topic><topic>Tubes for determining the presence, intensity, density or energy of radiation or particles</topic><topic>Visible spectra</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Therriault-Proulx, François</creatorcontrib><creatorcontrib>Beddar, Sam</creatorcontrib><creatorcontrib>Beaulieu, Luc</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Therriault-Proulx, François</au><au>Beddar, Sam</au><au>Beaulieu, Luc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>On the use of a single-fiber multipoint plastic scintillation detector for 192Ir high-dose-rate brachytherapy</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2013-06</date><risdate>2013</risdate><volume>40</volume><issue>6</issue><spage>062101</spage><epage>n/a</epage><pages>062101-n/a</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><eissn>0094-2405</eissn><coden>MPHYA6</coden><abstract>Purpose: The goal of this study was to prove the feasibility of using a single-fiber multipoint plastic scintillation detector (mPSD) as anin vivo verification tool during 192Ir high-dose-rate brachytherapy treatments. Methods: A three-point detector was built and inserted inside a catheter-positioning template placed in a water phantom. A hyperspectral approach was implemented to discriminate the different optical signals composing the light output at the exit of the single collection optical fiber. The mPSD was tested with different source-to-detector positions, ranging from 1 to 5 cm radially and over 10.5 cm along the longitudinal axis of the detector, and with various integration times. Several strategies for improving the accuracy of the detector were investigated. The device's accuracy in detecting source position was also tested. Results: Good agreement with the expected doses was obtained for all of the scintillating elements, with average relative differences from the expected values of 3.4 ± 2.1%, 3.0 ± 0.7%, and 4.5 ± 1.0% for scintillating elements from the distal to the proximal. A dose threshold of 3 cGy improved the general accuracy of the detector. An integration time of 3 s offered a good trade-off between precision and temporal resolution. Finally, the mPSD measured the radioactive source positioning uncertainty to be no more than 0.32 ± 0.06 mm. The accuracy and precision of the detector were improved by a dose-weighted function combining the three measurement points and known details about the geometry of the detector construction. Conclusions: The use of a mPSD for high-dose-rate brachytherapy dosimetry is feasible. This detector shows great promise for development ofin vivo applications for real-time verification of treatment delivery.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>23718599</pmid><doi>10.1118/1.4803510</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection
subjects Biomedical instrumentation and transducers, including micro‐electro‐mechanical systems (MEMS)
brachytherapy
Brachytherapy - instrumentation
Calibration
catheters
Catheters
Hollow probes
dosimetry
Dosimetry/exposure assessment
Equipment Design
Equipment Failure Analysis
Error analysis
Fiber Optic Technology - instrumentation
HDR brachytherapy
Infrared detectors
Infrared sources
Infrared spectra
Iridium Radioisotopes - analysis
Iridium Radioisotopes - therapeutic use
Measurement of nuclear or x‐radiation
multipoint detector
phantoms
plastic scintillation detector
Plastics - radiation effects
Position sensitive detectors
Radiation Measurement Physics
Radiation therapy
Radiotherapy Dosage
Reproducibility of Results
Scintillation Counting - instrumentation
Scintillation detectors
Sensitivity and Specificity
solid scintillation detectors
spectrometry
Therapeutic applications, including brachytherapy
Tubes for determining the presence, intensity, density or energy of radiation or particles
Visible spectra
title On the use of a single-fiber multipoint plastic scintillation detector for 192Ir high-dose-rate brachytherapy
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